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  1. No Access

    Article

    The prognostic impact of serum testosterone during androgen-deprivation therapy in patients with metastatic prostate cancer and the SRD5A2 polymorphism

    Although testosterone suppression during androgen-deprivation therapy (ADT) and obesity have been reported to affect ADT efficacy, there are few comprehensive analyses on the impact on ADT outcome. Recently, w...

    M Shiota, N Fujimoto, A Yokomizo, A Takeuchi… in Prostate Cancer and Prostatic Diseases (2016)

  2. No Access

    Article

    Laparoscopic en bloc excision of gastrointestinal stromal tumors of the rectum after neoadjuvant imatinib therapy: anteriorly extended intersphincteric resection combined with partial resection of the prostate

    We herein present a novel technique for laparoscopic en bloc excision involving anteriorly extended intersphincteric resection with partial resection of the posterior lobe of the prostate for large rectal gast...

    T. Ueki, K. Nagayoshi, T. Manabe, R. Maeyama, A. Yokomizo… in Techniques in Coloproctology (2015)

  3. No Access

    Article

    EP2 signaling mediates suppressive effects of celecoxib on androgen receptor expression and cell proliferation in prostate cancer

    Non-steroidal anti-inflammatory drugs inhibit the activity of cyclooxygenases (COXs), and their usage reduces the risks associated with prostate cancer. Celecoxib is a selective COX-2 inhibitor and reported to...

    E Kashiwagi, M Shiota, A Yokomizo, J Inokuchi… in Prostate Cancer and Prostatic Diseases (2014)

  4. No Access

    Article

    Castration resistance of prostate cancer cells caused by castration-induced oxidative stress through Twist1 and androgen receptor overexpression

    There are few successful therapies for castration-resistant prostate cancer (CRPC). Recently, CRPC has been thought to result from augmented androgen/androgen receptor (AR) signaling pathway, for most of which...

    M Shiota, A Yokomizo, Y Tada, J Inokuchi, E Kashiwagi, D Masubuchi, M Eto… in Oncogene (2010)