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Article
Open AccessClostridioides difficile toxin is infrequently detected in inflammatory bowel disease and does not associate with clinical outcomes
Clostridioides difficile infection (CDI) rates and outcomes can vary based on differences in testing strategy. Our aim was to assess the prevalence of toxin detection in inflammatory bowel disease (IBD) when comp...
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Article
Open AccessPrediction of life-story narrative for end-of-life surrogate’s decision-making is inadequate: a Q-methodology study
Substituted judgment assumes adequate knowledge of patient’s mind-set. However, surrogates’ prediction of individual healthcare decisions is often inadequate and may be based on shared background rather than p...
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Article
Balancing the Checkpoint: Managing Colitis Associated with Dual Checkpoint Inhibitors and High-Dose Aspirin
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Article
Tumor lysis syndrome and metastatic melanoma
Tumor lysis syndrome (TLS) is a potential emergent complication of oncologic treatment. TLS is commonly reported in hematological malignancies with rapid cell turnover rates, but is relatively rare in solid tu...
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Article
Open AccessInformation disclosure in clinical informed consent: “reasonable” patient’s perception of norm in high-context communication culture
The current doctrine of informed consent for clinical care has been developed in cultures characterized by low-context communication and monitoring-style co**. There are scarce empirical data on patients’ no...
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Article
Open AccessPatients’ perceived purpose of clinical informed consent: Mill’s individual autonomy model is preferred
Although informed consent is an integral part of clinical practice, its current doctrine remains mostly a matter of law and mainstream ethics rather than empirical research. There are scarce empirical data on ...
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Article
Open AccessInteraction between drug and placebo effects: a cross-over balanced placebo design trial
The total effect of a medication is the sum of its drug effect, placebo effect (meaning response), and their possible interaction. Current interpretation of clinical trials' results assumes no interaction. Dem...
