23 Result(s)
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Muhammad M. Hammami
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Article
Open AccessQuality assessment of nine paracetamol 500 mg tablet brands marketed in Saudi Arabia
To evaluate in-vitro quality of paracetamol 500 mg tablet brands marketed in Saudi Arabia.
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Open AccessMisleading localization by 18F-fluorocholine PET/CT in familial hypocalciuric hypercalcemia type-3: a case report
Familial hypocalciuric hypercalcemia (FHH) is a heterogeneous autosomal-dominant disorder of calcium hemostasis that may be difficult to distinguish clinically from mild primary hyperparathyroidism. Loss-of-fu...
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Open AccessPharmaceutical quality of seven brands of diclofenac tablet on the Saudi market
We previously reported the pharmaceutical quality of eight brands of 50 mg enteric-coated diclofenac sodium tablet available on the Saudi market. Here, we assess the quality of reference (R1) and four generic ...
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Open AccessEight enteric-coated 50 mg diclofenac sodium tablet formulations marketed in Saudi Arabia: in vitro quality evaluation
To evaluate in vitro quality of enteric-coated 50 mg diclofenac sodium tablet formulations on Saudi market.
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Open AccessFactors underlying surrogate medical decision-making in middle eastern and east Asian women: a Q-methodology study
It is not clear how lay people prioritize the various, sometimes conflicting, interests when they make surrogate medical decisions, especially in non-Western cultures. The extent such decisions are perspective...
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Open AccessPrediction of life-story narrative for end-of-life surrogate’s decision-making is inadequate: a Q-methodology study
Substituted judgment assumes adequate knowledge of patient’s mind-set. However, surrogates’ prediction of individual healthcare decisions is often inadequate and may be based on shared background rather than p...
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Open AccessVitamin-D2 treatment-associated decrease in 25(OH)D3 level is a reciprocal phenomenon: a randomized controlled trial
Vitamin-D2 (D2) treatment has been associated with a decrease in 25-hydroxy (25(OH)) vitamin-D3 (D3) level, suggesting that D3 treatment would be preferred to raise total 25(OH) vitamin-D (D) level. We postula...
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Open AccessGeneric-reference and generic-generic bioequivalence of forty-two, randomly-selected, on-market generic products of fourteen immediate-release oral drugs
The extents of generic-reference and generic-generic average bioequivalence and intra-subject variation of on-market drug products have not been prospectively studied on a large scale.
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Open AccessDoes the placebo effect modulate drug bioavailability? Randomized cross-over studies of three drugs
Medication effect is the sum of its drug, placebo, and drug*placebo interaction effects. It is conceivable that the interaction effect involves modulating drug bioavailability; it was previously observed that ...
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Article
Open AccessDifferential effects of vitamin D2 and D3 supplements on 25-hydroxyvitamin D level are dose, sex, and time dependent: a randomized controlled trial
Vitamin D (D) supplements are indispensable for its world-wide deficiency. Controversy continues on ergocalciferol (D2) and cholecalciferol (D3) relative potency as well as on dosing-schedule and sex role in r...
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Open AccessDrug*placebo interaction effect may bias clinical trials interpretation: hybrid balanced placebo and randomized placebo-controlled design
Conventional randomized placebo-controlled study design assumes the absence of drug*placebo interaction. We hypothesized the presence of such an interaction and that conventionally estimated drug effect might ...
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Open AccessExploring end of life priorities in Saudi males: usefulness of Q-methodology
Quality end-of-life care depends on understanding patients’ end-of-life choices. Individuals and cultures may hold end-of-life priorities at different hierarchy. Forced ranking rather than independent rating, ...
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Open AccessCase report of severe Cushing’s syndrome in medullary thyroid cancer complicated by functional diabetes insipidus, aortic dissection, jejunal intussusception, and paraneoplastic dysautonomia: remission with sorafenib without reduction in cortisol concentration
Normalization of cortisol concentration by multikinase inhibitors have been reported in three patients with medullary thyroid cancer-related Cushing’s syndrome. Aortic dissection has been reported in three pat...
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Open AccessInformation disclosure in clinical informed consent: “reasonable” patient’s perception of norm in high-context communication culture
The current doctrine of informed consent for clinical care has been developed in cultures characterized by low-context communication and monitoring-style co**. There are scarce empirical data on patients’ no...
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Open AccessPatients’ perceived purpose of clinical informed consent: Mill’s individual autonomy model is preferred
Although informed consent is an integral part of clinical practice, its current doctrine remains mostly a matter of law and mainstream ethics rather than empirical research. There are scarce empirical data on ...
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Open AccessAcute severe hypothyroidism is not associated with hyponatremia even with increased water intake: a prospective study in thyroid cancer patients
Hypothyroidism, commonly induced in preparation for radioiodine treatment of differentiated thyroid cancer, is a text-book cause for hyponatremia. Nausea, stress, and increased fluid intake associated with the...
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Open AccessConsenting options for posthumous organ donation: presumed consent and incentivesare not favored
Posthumous organ procurement is hindered by the consenting process. Several consenting systems have been proposed. There is limited information on public relative attitudes towards various consenting systems, ...
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Open AccessInteraction between drug and placebo effects: a cross-over balanced placebo design trial
The total effect of a medication is the sum of its drug effect, placebo effect (meaning response), and their possible interaction. Current interpretation of clinical trials' results assumes no interaction. Dem...
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Open AccessSaudi views on consenting for research on medical records and leftover tissue samples
Consenting for retrospective medical records-based research (MR) and leftover tissue-based research (TR) continues to be controversial. Our objective was to survey Saudis attending outpatient clinics at a tert...
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Open AccessWhich medical error to disclose to patients and by whom? Public preference and perceptions of norm and current practice
Disclosure of near miss medical error (ME) and who should disclose ME to patients continue to be controversial. Further, available recommendations on disclosure of ME have emerged largely in Western culture; t...
