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Article
Open AccessDetection of COVID-19 by quantitative analysis of carbonyl compounds in exhaled breath
COVID-19 has caused a worldwide pandemic, creating an urgent need for early detection methods. Breath analysis has shown great potential as a non-invasive and rapid means for COVID-19 detection. The objective ...
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Article
Open AccessClostridioides difficile toxin is infrequently detected in inflammatory bowel disease and does not associate with clinical outcomes
Clostridioides difficile infection (CDI) rates and outcomes can vary based on differences in testing strategy. Our aim was to assess the prevalence of toxin detection in inflammatory bowel disease (IBD) when comp...
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Article
Open AccessInduction of interferon response by high viral loads at early stage infection may protect against severe outcomes in COVID-19 patients
Key elements for viral pathogenesis include viral strains, viral load, co-infection, and host responses. Several studies analyzing these factors in the function of disease severity of have been published; howe...
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Article
How Antibiotics Should be Prescribed to Hospitalized Elderly Patients with Community-Acquired Pneumonia
Elderly patients hospitalized with community-acquired pneumonia (CAP) should be administered antimicrobials in the emergency department prior to transfer to the ward or intensive care unit (ICU). For ward pati...
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Article
Open AccessCost effectiveness of adherence to IDSA/ATS guidelines in elderly patients hospitalized for Community-Aquired Pneumonia
Adherence to guidelines for the treatment of hospitalized elderly patients with community-acquired pneumonia (CAP) has been associated with improved clinical outcomes. This study evaluated the cost-effectivene...
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Article
Macrolide Use and Neutrophil Function/Cytokine Levels in Hospitalized Patients with Community-Acquired Pneumonia: A Pilot Study
The objective of this study was to measure plasma cytokine levels and blood neutrophil functions as well as clinical outcomes in hospitalized patients with community-acquired pneumonia (CAP) treated with or wi...
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Article
Open AccessThe upper respiratory tract microbiome of hospitalised patients with community-acquired pneumonia of unknown aetiology: a pilot study
The composition of the upper respiratory tract microbiome may play an important role in the development of lower respiratory tract infections. Here, we characterised the microbiome of the nasopharynx and oroph...
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Article
Contrasting Inflammatory Responses in Severe and Non-severe Community-acquired Pneumonia
The objective of this study was to compare systemic and local cytokine profiles and neutrophil responses in patients with severe versus non-severe community-acquired pneumonia (CAP). Hospitalized patients with CA...
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Article
Clinico-Pathologic Conference: Case 3