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Article
Cyclophosphamide-modified murine peritoneal macrophages induce CD4+ T contrasuppressor cells that protect contact sensitivity T effector cells from suppression
Cyclophosphamide (CY) is one of the most widely used alkylating agents in the treatment of various cancers and some autoimmune diseases. Numerous reports suggest that CY exerts immunoregulatory effects. Animal...
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Article
Erratum to “Epicutaneous immunization with phosphorylcholine conjugated to bovine serum albumin (PC-BSA) and TLR9 ligand CpG alleviates pneumococcal pneumonia in mice”
The authors wish to note an incorrectly listed financial support grant. The National Science Centre grants 2011/01/B/NZ6/00300 and 2012/05/B/NZ6/00997 were inadvertently listed. The authors regret this error. ...
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Article
Erratum to “Partial depletion of natural gut flora by antibiotic aggravates collagen induced arthritis (CIA) in mice”
The authors wish to note an incorrectly listed financial support grants 2011/01/B/NZ6/00300 and 2011/03/B/NZ6/00801. The National Science Centre grants were inadvertently listed. The authors regret this error.
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Article
Erratum to “Oral treatment with enrofloxacin early in life promotes Th2-mediated immune response in mice”
The authors wish to note an incorrectly listed financial support grants. The National Science Centre grants 2011/01/B/NZ6/00300 and 2012/05/B/NZ6/00997 were inadvertently listed. The authors regret this error....
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Article
Erratum to “Inhibition of 2,4-dinitrofluorobenzene-induced contact hypersensitivity reaction by antidepressant drugs”
The authors wish to note an incorrectly listed financial support grant. The National Science Centre grant 2011/01/B/NZ6/00300 was inadvertently listed. The authors regret this error. The correct Acknowledgemen...
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Article
Erratum to “Epicutaneous immunization with protein antigen TNP-Ig alleviates TNBS-induced colitis in mice”
The authors wish to note an incorrectly listed financial support grant. The National Science Centre grant UMO-2011/01/B/NZ6/00300 was inadvertently listed. The authors regret this error. The correct Acknowledg...
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Article
Erratum to “Epicutaneous immunization with protein antigen TNP-Ig and NOD2 ligand muramyl dipeptide (MDP) reverses skin-induced suppression of contact hypersensitivity”
The authors wish to note an incorrectly listed financial support grant. The National Science Centre grants UMO-2012/05/B/NZ6/00997 and UMO-2011/03/B/NZ6/00821 were inadvertently listed. The authors regret this...
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Article
Erratum to “Epicutaneous immunization with hapten-conjugated protein antigen alleviates contact sensitivity mediated by three different types of effector cells”
The authors wish to note an incorrectly listed financial support grant. The National Science Centre grant 2011/01/B/NZ6/00300 was inadvertently listed. The authors regret this error. The correct Acknowledgemen...
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Article
Transdermal immunotherapy: Past, present and future
The human skin plays an important role in thermal regulation, the maintenance of the correct water and electrolyte balance; it is also the main source of the vitamin D for the organism. Moreover, the skin form...
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Article
Epicutaneous (EC) immunization with type II collagen (COLL II) induces CD4+ CD8+ T suppressor cells that protect from collagen-induced arthritis (CIA)
We have shown previously that epicutaneous (EC) immunization with protein antigen induces T suppressor cells that alleviate inflammatory response in contact hypersensitivity reactions, in an animal model of mu...
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Article
Oral treatment with enrofloxacin early in life promotes Th2-mediated immune response in mice
Th2 lymphocytes play a crucial role in the development of allergy. These pathologies are caused by coordinated production of the cytokines IL-4, IL-5 and IL-13 that regulate the activity of eosinophils, basoph...
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Article
Epicutaneous immunization with phosphorylcholine conjugated to bovine serum albumin (PC-BSA) and TLR9 ligand CpG alleviates pneumococcal pneumonia in mice
Epicutaneous (EC) immunization is a potential new strategy of a needle-free and self-administrable immunization by using a topically applied patch to deliver vaccine. We have previously shown that EC immunizat...
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Article
Partial depletion of natural gut flora by antibiotic aggravates collagen induced arthritis (CIA) in mice
Rheumatoid arthritis (RA) is a chronic inflammatory disease that affects about 1% of the adult population and occurs twice as frequently among women than men. At present it is accepted that pathogenesis of RA ...
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Article
Epicutaneous immunization with protein antigen TNP-Ig and NOD2 ligand muramyl dipeptide (MDP) reverses skin-induced suppression of contact hypersensitivity
Epicutaneous (EC) immunization offers a new method of a needle-free and self-administrable immunization by using a topically applied patch to deliver vaccine.
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Article
Inhibition of 2,4-dinitrofluorobenzene-induced contact hypersensitivity reaction by antidepressant drugs
Contact hypersensitivity (CHS) induced by a topical application of hapten - 2,4-dinitrofluorobenzene (DNFB), is a T cytotoxic (Tc)1-cell-mediated antigen-specific type of skin inflammation. Recently, it has be...
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Article
Epicutaneous immunization with protein antigen induces antigen-non-specific suppression of CD8 T cell mediated contact sensitivity
Allergic contact dermatitis (ACD) resulting from exposure to low molecular weight chemicals is a common clinical condition in industrialized countries and can be mediated by either Th1 or Tc1 lymphocytes. The ...
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Article
Epicutaneous immunization with protein antigen TNP-Ig alleviates TNBS-induced colitis in mice
Ulcerative colitis (UC) is a chronic inflammatory autoimmune disease with limited treatment modalities. The animal model of colitis induced by treatment with trinitrobenzene sulfonic acid (TNBS-colitis) is com...
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Article
Epicutaneous immunization with hapten-conjugated protein antigen alleviates contact sensitivity mediated by three different types of effector cells
Allergic contact dermatitis (ACD) is a common clinical condition in industrialized countries and often causes occupational diseases. Animal model of contact sensitivity (CS) is commonly used to study ACD in mi...
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Article
Inhibitory effect of antidepressant drugs on contact hypersensitivity reaction
Contact hypersensitivity (CS) reaction in the skin is T-cell mediated immune reaction which plays a major role in the pathogenesis and chronicity of various inflammatory skin disorders and, like other delayed-...