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  1. No Access

    Article

    Virus/Allergen Interactions in Asthma

    Understanding the underlying mechanisms that cause and exacerbate allergic asthmatic disease is of great clinical interest. Clinical studies have revealed that allergies and viral respiratory illnesses are str...

    Monica L. Gavala, Hiba Bashir, James E. Gern in Current Allergy and Asthma Reports (2013)

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    Article

    Transcriptional control mechanisms associated with the nucleotide receptor P2X7, a critical regulator of immunologic, osteogenic, and neurologic functions

    The nucleotide receptor P2X7 is an attractive therapeutic target and potential biomarker for multiple inflammatory and neurologic disorders, and it is expressed in several immune, osteogenic, and neurologic cell ...

    Lisa Y. Lenertz, Monica L. Gavala, Yiming Zhu, Paul J. Bertics in Immunologic Research (2011)

  3. No Access

    Article

    Cell signaling via the P2X7 nucleotide receptor: linkage to ROS production, gene transcription, and receptor trafficking

    Extracellular nucleotides can act as important intercellular signals in diverse biological processes, including the enhanced production of factors that are key to immune response regulation. One receptor that ...

    Lisa Y. Lenertz, Monica L. Gavala, Lindsay M. Hill in Purinergic Signalling (2009)

  4. Article

    Open Access

    Nucleotide receptor signalling and the generation of reactive oxygen species

    Elevated levels of extracellular nucleotides are present at sites of inflammation, platelet degranulation and cellular damage or lysis. These extracellular nucleotides can lead to the activation of purinergic ...

    Alma N. Guerra, Monica L. Gavala, Hun Sun Chung, Paul J. Bertics in Purinergic Signalling (2007)