7 Result(s)

Article

FRMD6 determines the cell fate towards senescence: involvement of the Hippo-YAP-CCN3 axis

Cellular senescence, a hallmark of aging, is pathogenically linked to the development of aging-related diseases. This study demonstrates that FRMD6, an upstream component of the Hippo/YAP signaling cascade, is...

Jung-** Park, Su ** Lee, Minwoo Baek, Ok-Jun Lee… in Cell Death & Differentiation (2024)

Article

Modeling pressure drop values across ultra-thin nanofiber filters with various ranges of filtration parameters under an aerodynamic slip effect

Computational fluid dynamics simulations of fibrous filters with 56 combinations of different fiber sizes, packing densities, face velocities, and thicknesses were conducted for develo** models that predict ...

Songhui Lee, Dai Bui-Vinh, Minwoo Baek, Dong-Bin Kwak, Handol Lee in Scientific Reports (2023)

Article

Author Correction: TDP-43 and PINK1 mediate CHCHD10^S59L mutation–induced defects in Drosophila and in vitro

Minwoo Baek, Yun-Jeong Choe, Sylvie Bannwarth, JiHye Kim… in Nature Communications (2021)

Article

TDP-43 and PINK1 mediate CHCHD10^S59L mutation–induced defects in Drosophila and in vitro

Mutations in coiled-coil-helix-coiled-coil-helix domain containing 10 (CHCHD10) can cause amyotrophic lateral sclerosis and frontotemporal dementia (ALS-FTD). However, the underlying mechanisms are unclear. Here,...

Minwoo Baek, Yun-Jeong Choe, Sylvie Bannwarth, JiHye Kim… in Nature Communications (2021)

Article

Epidermal-specific deletion of TC-PTP promotes UVB-induced epidermal cell survival through the regulation of Flk-1/JNK signaling

UVB exposure can contribute to the development of skin cancer by modulating protein tyrosine kinase (PTK) signaling. It has been suggested that UVB radiation increases the ligand-dependent activation of PTKs a...

Minwoo Baek, Mihwa Kim, Jae Sung Lim, Liza D. Morales… in Cell Death & Disease (2018)

Article

Duox mediates ultraviolet injury-induced nociceptive sensitization in Drosophila larvae

Nociceptive sensitization is an increase in pain perception in response to stimulus. Following brief irradiation of Drosophila larvae with UV, nociceptive sensitization occurs in class IV multiple dendritic (mdIV...

Wijeong Jang, Minwoo Baek, Yeon Soo Han, Changsoo Kim in Molecular Brain (2018)

Article

Targeted disruption of TC-PTP in the proliferative compartment augments STAT3 and AKT signaling and skin tumor development

Tyrosine phosphorylation is a vital mechanism that contributes to skin carcinogenesis. It is regulated by the counter-activities of protein tyrosine kinases (PTKs) and protein tyrosine phosphatases (PTPs). Her...

Hyunseung Lee, Mihwa Kim, Minwoo Baek, Liza D. Morales, Ik-Soon Jang… in Scientific Reports (2017)