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  1. Article

    Open Access

    Myomerger induces fusion of non-fusogenic cells and is required for skeletal muscle development

    Despite the importance of cell fusion for mammalian development and physiology, the factors critical for this process remain to be fully defined, which has severely limited our ability to reconstitute cell fus...

    Malgorzata E. Quinn, Qingnian Goh, Mitsutoshi Kurosaka in Nature Communications (2017)

  2. Article

    Open Access

    Single-nucleus RNA-seq identifies transcriptional heterogeneity in multinucleated skeletal myofibers

    While the majority of cells contain a single nucleus, cell types such as trophoblasts, osteoclasts, and skeletal myofibers require multinucleation. One advantage of multinucleation can be the assignment of dis...

    Michael J. Petrany, Casey O. Swoboda, Chengyi Sun, Kashish Chetal in Nature Communications (2020)