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Article
Open AccessAntiviral activity of marine sulfated glycans against pathogenic human coronaviruses
Great interest exists towards the discovery and development of broad-spectrum antivirals. This occurs due to the frequent emergence of new viruses which can also eventually lead to pandemics. A reasonable and ...
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Article
Open AccessGenome sequences of human cytomegalovirus strain TB40/E variants propagated in fibroblasts and epithelial cells
The advent of whole genome sequencing has revealed that common laboratory strains of human cytomegalovirus (HCMV) have major genetic deficiencies resulting from serial passage in fibroblasts. In particular, tr...
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Article
Open AccessCorrection to: Human cytomegalovirus DNA and immediate early protein 1/2 are highly associated with glioma and prognosis
In the original publication the email addresses of corresponding authors have not been displayed. The correct email addresses of corresponding authors are provided in this correction. Fang-Cheng Li (sjwklfc@12...
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Article
Impairment in neurocognitive function following experimental neonatal guinea pig cytomegalovirus infection
Cytomegalovirus (CMV) is a leading infectious cause of neurologic deficits, both in the settings of congenital and perinatal infection, but few animal models exist to study neurodevelopmental outcomes. This st...
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Article
Open AccessHuman cytomegalovirus DNA and immediate early protein 1/2 are highly associated with glioma and prognosis
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Article
Open AccessComparative neutralizing potencies of antibodies suggest conservation as well as mechanistic differences in human cytomegalovirus entry into epithelial and endothelial cells
Antibody neutralization of cytomegalovirus (CMV) entry into diverse cell types is a key consideration for development of vaccines and immunotherapeutics. CMV entry into fibroblasts differs significantly from e...
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Article
Genomic analysis of chimeric human cytomegalovirus vaccine candidates derived from strains Towne and Toledo
Human cytomegalovirus (HCMV) is an important opportunistic pathogen in immunocompromised patients and a major cause of congenital birth defects when acquired in utero. In the 1990s, four chimeric viruses were ...
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Article
Open AccessChanges in subcellular localization reveal interactions between human cytomegalovirus terminase subunits
During herpesvirus replication, terminase packages viral DNA into capsids. The subunits of herpes simplex virus terminase, UL15, UL28, and UL33, assemble in the cytoplasm prior to nuclear import of the complex.
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Article
Open AccessIntravaginal cytomegalovirus (CMV) challenge elicits maternal viremia and results in congenital transmission in a guinea pig model
The objective of this study was to compare intravaginal (ivg) and subcutaneous (sc) administration of the guinea pig cytomegalovirus (GPCMV) in pregnant and non-pregnant guinea pigs. These studies tested the h...
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Article
Open AccessAnalysis of the nucleotide sequence of the guinea pig cytomegalovirus (GPCMV) genome
In this report we describe the genomic sequence of guinea pig cytomegalovirus (GPCMV) assembled from a tissue culture-derived bacterial artificial chromosome clone, plasmid clones of viral restriction fragment...
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Chapter
Packaging DNA into Herpesvirus Capsids