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Article
Open AccessUse of Different Process Gases for Manufacturing Isolating Alumina Coatings by Flame Spraying with Cords
Besides conventional industrial demands, thermally sprayed coatings are increasingly used for innovative products. Such an application is the additive manufacturing of electrical components in automotive engin...
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Article
Synthesis facilitates an understanding of the structural basis for translation inhibition by the lissoclimides
The lissoclimides are unusual succinimide-containing labdane diterpenoids that were reported to be potent cytotoxins. Our short semisynthesis and analogue-oriented synthesis approaches provide a series of liss...
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Article
Is Financial Literacy a Determinant of Health?
Changes in economic conditions and healthcare delivery models have shifted more healthcare costs to patients, resulting in greater patient financial responsibilities. As a result, it is important to understand...
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Article
High platelet reactivity after P2Y12-inhibition in patients with atrial fibrillation and coronary stenting
High platelet reactivity (HPR) after P2Y12-inhibition in patients undergoing coronary stenting is associated with an increased risk for thromboembolic events and coronary death. So far it is not known how HPR aff...
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Article
Dabigatran and rivaroxaban do not affect AA- and ADP-induced platelet aggregation in patients receiving concomitant platelet inhibitors
Dabigatran and rivaroxaban are novel, vitamin K-independent oral anticoagulants (NOACs) and act via antagonism of the coagulation factor (F) IIa (dabigatran) or FXa (rivaroxaban), respectively. Compared to vit...
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Protocol
Polyacrylamide Gel Electrophoresis for Purification of Large Amounts of RNA
Polyacrylamide gel electrophoresis (PAGE) constitutes a powerful technique for the efficient purification of RNA molecules dedicated to applications that require high purity levels. PAGE allows for the fractio...
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Protocol
Cis-Acting 5’ Hammerhead Ribozyme Optimization for In Vitro Transcription of Highly Structured RNAs
RNA-mediated biological processes usually require precise definition of 5′ and 3′ ends. RNA ends obtained by in vitro transcription using T7 RNA polymerase are often heterogeneous in length and sequence. An ef...
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Article
Gezielte Manipulation des Genoms mit Zinkfingernukleasen
In vielen Säugetierarten gab es bis jetzt keine effektiven Werkzeuge für eine gezielte Genmodifikation. Die Entwicklung der Zinkfingernuklease-Technologie ermöglicht nun auch in diesen Organismen eine schnelle...