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  1. Article

    Open Access

    Addressing data limitations in seizure prediction through transfer learning

    According to the literature, seizure prediction models should be developed following a patient-specific approach. However, seizures are usually very rare events, meaning the number of events that may be used t...

    Fábio Lopes, Mauro F. Pinto, António Dourado, Andreas Schulze-Bonhage in Scientific Reports (2024)

  2. Article

    Open Access

    Comparison between epileptic seizure prediction and forecasting based on machine learning

    Epilepsy affects around 1% of the population worldwide. Anti-epileptic drugs are an excellent option for controlling seizure occurrence but do not work for around one-third of patients. Warning devices employi...

    Gonçalo Costa, César Teixeira, Mauro F. Pinto in Scientific Reports (2024)

  3. Article

    Open Access

    EEG epilepsy seizure prediction: the post-processing stage as a chronology

    Almost one-third of epileptic patients fail to achieve seizure control through anti-epileptic drug administration. In the scarcity of completely controlling a patient’s epilepsy, seizure prediction plays a sig...

    Joana Batista, Mauro F. Pinto, Mariana Tavares, Fábio Lopes in Scientific Reports (2024)

  4. Article

    Open Access

    Removing artefacts and periodically retraining improve performance of neural network-based seizure prediction models

    The development of seizure prediction models is often based on long-term scalp electroencephalograms (EEGs) since they capture brain electrical activity, are non-invasive, and come at a relatively low-cost. Ho...

    Fábio Lopes, Adriana Leal, Mauro F. Pinto, António Dourado in Scientific Reports (2023)

  5. Article

    Open Access

    Unsupervised EEG preictal interval identification in patients with drug-resistant epilepsy

    Typical seizure prediction models aim at discriminating interictal brain activity from pre-seizure electrographic patterns. Given the lack of a preictal clinical definition, a fixed interval is widely used to ...

    Adriana Leal, Juliana Curty, Fábio Lopes, Mauro F. Pinto in Scientific Reports (2023)

  6. Article

    Open Access

    EPIC: Annotated epileptic EEG independent components for artifact reduction

    Scalp electroencephalogram is a non-invasive multi-channel biosignal that records the brain’s electrical activity. It is highly susceptible to noise that might overshadow important data. Independent component ...

    Fábio Lopes, Adriana Leal, Júlio Medeiros, Mauro F. Pinto in Scientific Data (2022)

  7. Article

    Open Access

    Heart rate variability analysis for the identification of the preictal interval in patients with drug-resistant epilepsy

    Electrocardiogram (ECG) recordings, lasting hours before epileptic seizures, have been studied in the search for evidence of the existence of a preictal interval that follows a normal ECG trace and precedes th...

    Adriana Leal, Mauro F. Pinto, Fábio Lopes, Anna M. Bianchi in Scientific Reports (2021)

  8. Article

    Open Access

    A personalized and evolutionary algorithm for interpretable EEG epilepsy seizure prediction

    Seizure prediction may improve the quality of life of patients suffering from drug-resistant epilepsy, which accounts for about 30% of the total epileptic patients. The pre-ictal period determination, characte...

    Mauro. F. Pinto, Adriana Leal, Fábio Lopes, António Dourado in Scientific Reports (2021)

  9. Article

    Open Access

    Prediction of disease progression and outcomes in multiple sclerosis with machine learning

    Multiple Sclerosis is a chronic inflammatory disease, affecting the Central Nervous System and leading to irreversible neurological damage, such as long term functional impairment and disability. It has no cur...

    Mauro F. Pinto, Hugo Oliveira, Sónia Batista, Luís Cruz in Scientific Reports (2020)