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Open AccessHigh precision in epileptic seizure self-reporting with an app diary
People with epilepsy frequently under- or inaccurately report their seizures, which poses a challenge for evaluating their treatment. The introduction of epilepsy health apps provides a novel approach that cou...
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Open AccessAddressing data limitations in seizure prediction through transfer learning
According to the literature, seizure prediction models should be developed following a patient-specific approach. However, seizures are usually very rare events, meaning the number of events that may be used t...
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Open AccessErster epileptischer Anfall und Epilepsien im Erwachsenenalter
In der neuen S2k-Leitlinie „Erster epileptischer Anfall und Epilepsien im Erwachsenenalter“ werden Empfehlungen zu klinisch relevanten Fragestellungen in fünf großen Themenblöcken gegeben: Management erster ep...
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Open AccessTechnical note: preliminary surgical experience with a new implantable epicranial stimulation device for chronic focal cortex stimulation in drug-resistant epilepsy
This study is to report some preliminary surgical considerations and outcomes after the first implantations of a new and commercially available implantable epicranial stimulation device for focal epilepsy.
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Open AccessRipple-locked coactivity of stimulus-specific neurons and human associative memory
Associative memory enables the encoding and retrieval of relations between different stimuli. To better understand its neural basis, we investigated whether associative memory involves temporally correlated sp...
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Open AccessDynamic facial emotion recognition and affective prosody recognition are associated in patients with temporal lobe epilepsy
Deficits in facial emotion recognition have frequently been established in temporal lobe epilepsy (TLE). However, static, rather than dynamic emotion recognition paradigms have been applied. Affective prosody ...
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Efficacy of ictal neurostimulation—English version
Neurostimulation is an established procedure for the treatment of drug-resistant epilepsies, with results from controlled and uncontrolled clinical trials indicating neuromodulation-mediated efficacy that incr...
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Open AccessA Prospective Longitudinal Study of the Effects of Eslicarbazepine Acetate Treatment on Bone Density and Metabolism in Patients with Focal-Onset Epilepsy
Eslicarbazepine acetate (ESL) is a third-generation anti-seizure medication for patients with focal-onset epilepsy. There are known short-term impacts of classic enzyme-inducing drugs on bone health. For oxcar...
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Open AccessDiagnostic Accuracy of Epilepsy-dedicated MRI with Post-processing
To evaluate the diagnostic accuracy of epilepsy-dedicated 3 Tesla MRI including post-processing by correlating MRI, histopathology, and postsurgical seizure outcomes.
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Open AccessRemoving artefacts and periodically retraining improve performance of neural network-based seizure prediction models
The development of seizure prediction models is often based on long-term scalp electroencephalograms (EEGs) since they capture brain electrical activity, are non-invasive, and come at a relatively low-cost. Ho...
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Open AccessWirksamkeit der iktalen Neurostimulation
Die Neurostimulation ist ein etabliertes Verfahren zur Behandlung pharmakoresistenter Epilepsien, wobei Ergebnisse aus kontrollierten und unkontrollierten klinischen Studien auf eine durch Neuromodulation verm...
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Comprehensive multi-omic profiling of somatic mutations in malformations of cortical development
Malformations of cortical development (MCD) are neurological conditions involving focal disruptions of cortical architecture and cellular organization that arise during embryogenesis, largely from somatic mosa...
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Open AccessData quality evaluation in wearable monitoring
Wearable recordings of neurophysiological signals captured from the wrist offer enormous potential for seizure monitoring. Yet, data quality remains one of the most challenging factors that impact data reliabi...
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Open AccessHow to identify insular epilepsy
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Open AccessIctal semiology of epileptic seizures with insulo-opercular genesis
Epileptic seizures with insular genesis are often difficult to distinguish from those originating in the temporal lobe due to their complex and variable semiology. Here, we analyzed differentiating characteris...
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Open Access“Within a minute” detection of focal cortical dysplasia
To evaluate a MRI postprocessing tool for the enhanced and rapid detection of focal cortical dysplasia (FCD).
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Open AccessEffect of Cannabidiol on Interictal Epileptiform Activity and Sleep Architecture in Children with Intractable Epilepsy: A Prospective Open-Label Study
Cannabidiol has been shown to be effective in seizure reduction in patients with Dravet syndrome, Lennox–Gastaut syndrome, and tuberous sclerosis. However, very little is known about its potential to reduce in...
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Open AccessFood intake precipitates seizures in temporal lobe epilepsy
Various factors have been considered as potential seizure precipitants. We here assessed the temporal association of food intake and seizure occurrence, and characteristics of seizures and epilepsy syndromes i...
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Open AccessSUDEP kompakt – praxisrelevante Erkenntnisse und Empfehlungen zum plötzlichen, unerwarteten Tod bei Epilepsie
„Sudden unexpected death in epilepsy“ (SUDEP) ist der plötzliche, unerwartete Tod eines Epilepsiepatienten, der unter „gutartigen“ Umständen und ohne typische Todesursachen auftritt. SUDEP betrifft alle Epilep...
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Open AccessImpfung zur Vorbeugung der COVID-19-Erkrankung sowie Impfpriorisierung bei Epilepsie
Der Vorstand der Deutschen Gesellschaft für Epileptologie und die Kommission „Epilepsie und Synkopen“ der Deutschen Gesellschaft für Neurologie haben die aktuelle Datenlage zur Impfung zur Vorbeugung der Coron...