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Article
Open AccessOptimizing EEG Source Reconstruction with Concurrent fMRI-Derived Spatial Priors
Reconstructing EEG sources involves a complex pipeline, with the inverse problem being the most challenging. Multiple inversion algorithms are being continuously developed, aiming to tackle the non-uniqueness ...
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Article
Open AccessPosttranslational modifications of proteins are key features in the identification of CSF biomarkers of multiple sclerosis
Multiple sclerosis is an inflammatory and degenerative disease of the central nervous system (CNS) characterized by demyelination and concomitant axonal loss. The lack of a single specific test, and the simila...
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Article
Clinical effectiveness of reduced fingolimod dose in relapsing remitting multiple sclerosis—a Portuguese cohort
Fingolimod is an oral daily treatment for relapsing remitting multiple sclerosis (RRMS). A decrease in lymphocytes count is a common side effect, whereby clinicians occasionally propose a reduced dose rather t...
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Article
Open AccessPrediction of disease progression and outcomes in multiple sclerosis with machine learning
Multiple Sclerosis is a chronic inflammatory disease, affecting the Central Nervous System and leading to irreversible neurological damage, such as long term functional impairment and disability. It has no cur...
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Article
Use of technological processing of seaweed and microalgae as strategy to improve their apparent digestibility coefficients in European seabass (Dicentrarchus labrax) juveniles
Algae are natural sources of nutrients, but the presence of anti-nutritional factors often compromises nutrient apparent digestibility coefficients (ADCs) in several fish species. In this study, physical-mecha...
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Article
Exploring the potential of seaweed Gracilaria gracilis and microalga Nannochloropsis oceanica, single or blended, as natural dietary ingredients for European seabass Dicentrarchus labrax
Gracilaria gracilis and Nannochloropsis oceanica, single or blended, were tested in European seabass (Dicentrarchus labrax) diets. A control (CTRL) diet was compared with experimental diets including either 8% G....
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Chapter and Conference Paper
Investigating Whole-Brain MRI Markers in Multiple Sclerosis – Emerging Dimensions in Morphometric Space
Magnetic resonance imaging (MRI) has become a crucial criterion for diagnosis and prognosis in early Multiple sclerosis (MS). Grey matter (GM) pathology has been described. However, little is known about the ...
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Article
Defatted microalgae (Nannochloropsis sp.) from biorefinery as a potential feed protein source to replace fishmeal in European sea bass diets
The present work focuses on the use of defatted biomass of the microalga Nannochloropsis sp. from the biodiesel industry, as a partial substitute of fish meal (FM) in diets for European sea bass. The effects of i...
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Chapter
Multiple Sclerosis: Implications of Obesity in Neuroinflammation
Since the discovery of the remarkable properties of adipose tissue as a metabolically active organ, several evidences on the possible link between obesity and the pathogenesis of multiple sclerosis (MS) have b...
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Article
Carotenoid deposition, flesh quality and immunological response of Nile tilapia fed increasing levels of IMTA-cultivated Ulva spp.
Increasing levels of a mixture of Ulva spp. (Ulva rigida and Ulva lactuca) produced in an integrated multi-trophic aquaculture (IMTA) system were evaluated in Nile tilapia. A control diet (CTRL) was compared with...
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Article
Open AccessThe Almirall European Headache Awards 2009
The Almirall European Headache Awards (AEHA) were organized in conjunction with the European Headache Federation. The awards were held in 2009, aiming to share clinical experience and best practice in headache...