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  1. Article

    Open Access

    Incidence of acute kidney injury and attributive mortality in acute respiratory distress syndrome randomized trials

    The development of acute kidney injury (AKI) after the acute respiratory distress syndrome (ARDS) reduces the chance of organ recovery and survival. The purpose of this study was to examine the AKI rate and at...

    Edoardo Antonucci, Bruno Garcia, David Chen, Michael A. Matthay in Intensive Care Medicine (2024)

  2. Article

    Open Access

    Correction: Mild increases in plasma creatinine after intermediate to high-risk abdominal surgery are associated with long-term renal injury

    Alexandre Joosten, Brigitte Ickx, Zakaria Mokhtari, Luc Van Obbergh in BMC Anesthesiology (2024)

  3. Article

    Using diuretic therapy in the critically ill patient

    Marlies Ostermann, Linda Awdishu, Matthieu Legrand in Intensive Care Medicine (2024)

  4. Article

    Serial lactate measurements to guide resuscitation: more evidence not to?

    Matthieu Legrand, Iwan C. C. van der Horst, Audrey De Jong in Intensive Care Medicine (2024)

  5. Article

    Open Access

    Sepsis-associated acute kidney injury: recent advances in enrichment strategies, sub-phenoty** and clinical trials

    Acute kidney injury (AKI) often complicates sepsis and is associated with high morbidity and mortality. In recent years, several important clinical trials have improved our understanding of sepsis-associated A...

    Matthieu Legrand, Sean M. Bagshaw, Pavan K. Bhatraju, Azra Bihorac in Critical Care (2024)

  6. No Access

    Article

    Acute kidney injury in patients with burns

    Burn injury is associated with a high risk of acute kidney injury (AKI) with a prevalence of AKI among patients with burns of 9–50%. Despite an improvement in burn injury survival in the past decade, AKI in pa...

    Matthieu Legrand, Audra T. Clark, Javier A. Neyra in Nature Reviews Nephrology (2024)

  7. Article

    Open Access

    An international RAND/UCLA expert panel to determine the optimal diagnosis and management of burn inhalation injury

    Burn inhalation injury (BII) is a major cause of burn-related mortality and morbidity. Despite published practice guidelines, no consensus exists for the best strategies regarding diagnosis and management of B...

    Helena Milton-Jones, Sabri Soussi, Roger Davies, Emmanuel Charbonney in Critical Care (2023)

  8. Article

    Open Access

    The alternative renin–angiotensin system in critically ill patients: pathophysiology and therapeutic implications

    The renin–angiotensin system (RAS) plays a crucial role in regulating blood pressure and the cardio-renal system. The classical RAS, mainly mediated by angiotensin I, angiotensin-converting enzyme, and angiote...

    Bruno Garcia, Alexander Zarbock, Rinaldo Bellomo, Matthieu Legrand in Critical Care (2023)

  9. No Access

    Article

    Subclinical and clinical acute kidney injury share similar urinary peptide signatures and prognosis

    Acute kidney injury (AKI) is a frequent and severe condition in intensive care units (ICUs). In 2020, the Acute Dialysis Quality Initiative (ADQI) group proposed a new stage of AKI, referred to as stage 1S, wh...

    Louis Boutin, Agnieszka Latosinska, Harald Mischak in Intensive Care Medicine (2023)

  10. Article

    Tackling sepsis-associated acute kidney injury using routinely collected data

    Rolando Claure-Del Granado, Matthew T. James, Matthieu Legrand in Intensive Care Medicine (2023)

  11. Article

    Open Access

    Adjunctive vasopressors in distributive shock: How soon is early?

    Bruno Garcia, Matthieu Legrand in Critical Care (2023)

  12. Article

    Open Access

    Could Repeated Cardio-Renal Injury Trigger Late Cardiovascular Sequelae in Extreme Endurance Athletes?

    Regular exercise confers multifaceted and well-established health benefits. Yet, transient and asymptomatic increases in markers of cardio-renal injury are commonly observed in ultra-endurance athletes during ...

    Johannes Burtscher, Paul-Emmanuel Vanderriele, Matthieu Legrand in Sports Medicine (2022)

  13. Article

    Differences in HADS and SF-36 scores 1 year after critical illness in COVID-19 patients

    Roberta Teixeira Tallarico, Benjamin Deniau, Nicholas Fong in Intensive Care Medicine (2022)

  14. Article

    Open Access

    Capillary refill time for the management of acute circulatory failure: a survey among pediatric and adult intensivists

    Recent studies have shown the prognostic value of capillary refill time (CRT) and suggested that resuscitation management guided by CRT may reduce morbidity and mortality in patients with septic shock. However...

    Matthias Jacquet-Lagrèze, Cléo Wiart, Rémi Schweizer, Léa Didier in BMC Emergency Medicine (2022)

  15. Article

    Correction to: Comparison of 8 versus 15 days of antibiotic therapy for Pseudomonas aeruginosa ventilator-associated pneumonia in adults: a randomized, controlled, open-label trial

    Adrien Bouglé, Sophie Tuffet, Laura Federici, Marc Leone in Intensive Care Medicine (2022)

  16. No Access

    Article

    Comparison of 8 versus 15 days of antibiotic therapy for Pseudomonas aeruginosa ventilator-associated pneumonia in adults: a randomized, controlled, open-label trial

    Duration of antibiotic therapy for ventilator-associated pneumonia (VAP) due to non-fermenting Gram-negative bacilli (NF-GNB), including Pseudomonas aeruginosa (PA) remains uncertain. We aimed to assess the non-i...

    Adrien Bouglé, Sophie Tuffet, Laura Federici, Marc Leone in Intensive Care Medicine (2022)

  17. Article

    Ten tips to optimize vasopressors use in the critically ill patient with hypotension

    Matthieu Legrand, Alexander Zarbock in Intensive Care Medicine (2022)

  18. Article

    Pathophysiology of COVID-19-associated acute kidney injury

    Although respiratory failure and hypoxaemia are the main manifestations of COVID-19, kidney involvement is also common. Available evidence supports a number of potential pathophysiological pathways through whi...

    Matthieu Legrand, Samira Bell, Lui Forni, Michael Joannidis in Nature Reviews Nephrology (2021)

  19. Article

    Ketamine-induced cholangiopathy in ARDS patients

    Christian de Tymowski, François Dépret, Emmanuel Dudoignon in Intensive Care Medicine (2021)

  20. Article

    Open Access

    Acute kidney injury in the critically ill: an updated review on pathophysiology and management

    Acute kidney injury (AKI) is now recognized as a heterogeneous syndrome that not only affects acute morbidity and mortality, but also a patient’s long-term prognosis. In this narrative review, an update on var...

    Peter Pickkers, Michael Darmon, Eric Hoste, Michael Joannidis in Intensive Care Medicine (2021)

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