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Article
‘Reviving’ the call for standardization of the composite outcome of major adverse kidney events in critical care nephrology research
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Article
Acute kidney injury in patients with burns
Burn injury is associated with a high risk of acute kidney injury (AKI) with a prevalence of AKI among patients with burns of 9–50%. Despite an improvement in burn injury survival in the past decade, AKI in pa...
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Article
Digital health and acute kidney injury: consensus report of the 27th Acute Disease Quality Initiative workgroup
Acute kidney injury (AKI), which is a common complication of acute illnesses, affects the health of individuals in community, acute care and post-acute care settings. Although the recognition, prevention and m...
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Article
Open AccessAcute kidney injury in neurocritical care
Approximately 20% of patients with acute brain injury (ABI) also experience acute kidney injury (AKI), which worsens their outcomes. The metabolic and inflammatory changes associated with AKI likely contribute...
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Article
Open AccessFluid balance and renal replacement therapy initiation strategy: a secondary analysis of the STARRT-AKI trial
Among critically ill patients with acute kidney injury (AKI), earlier initiation of renal replacement therapy (RRT) may mitigate fluid accumulation and confer better outcomes among individuals with greater flu...
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Article
Delivering optimal renal replacement therapy to critically ill patients with acute kidney injury
Critical illness is often complicated by acute kidney injury (AKI). In patients with severe AKI, renal replacement therapy (RRT) is deployed to address metabolic dysfunction and volume excess until kidney func...
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Article
Open AccessSerum IL-17 levels are higher in critically ill patients with AKI and associated with worse outcomes
Interleukin-17 (IL-17) antagonism in rats reduces the severity and progression of AKI. IL-17-producing circulating T helper-17 (TH17) cells is increased in critically ill patients with AKI indicating that this...
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Article
Open AccessAcute kidney injury contributes to worse physical and quality of life outcomes in survivors of critical illness
Survivors of critical illness and acute kidney injury (AKI) are at risk of increased morbidity. The purpose of this study was to compare physical, emotional, and cognitive health in survivors of critical illne...
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Article
Open AccessSerum renin and major adverse kidney events in critically ill patients: a multicenter prospective study
Preliminary studies have suggested that the renin-angiotensin system is activated in critical illness and associated with mortality and kidney outcomes. We sought to assess in a larger, multicenter study the r...
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Article
Open AccessDevelopment, implementation and outcomes of a quality assurance system for the provision of continuous renal replacement therapy in the intensive care unit
Critically ill patients with requirement of continuous renal replacement therapy (CRRT) represent a growing intensive care unit (ICU) population. Optimal CRRT delivery demands continuous communication between ...
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Article
Open AccessImpact of protocolized diuresis for de-resuscitation in the intensive care unit
Administration of diuretics has been shown to assist fluid management and improve clinical outcomes in the critically ill post-shock resolution. Current guidelines have not yet included standardization or guid...
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Article
Open AccessPacked red blood cell transfusion associates with acute kidney injury after transcatheter aortic valve replacement
Acute kidney injury after cardiac surgery significantly associates with morbidity and mortality. Despite not requiring cardiopulmonary bypass, transcatheter aortic valve replacement patients have an incidence ...
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Article
Open AccessEffect of hyperchloremia on acute kidney injury in critically ill septic patients: a retrospective cohort study
Hyperchloremia is common in critically ill septic patients. The impact of hyperchloremia on the incidence of acute kidney injury (AKI) is not well studied. We investigated the association between hyperchloremi...
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Article
Fibroblast growth factor 23 and acute kidney injury
Fibroblast growth factor 23 (FGF23), which is produced in bone, participates in the maintenance of phosphate metabolism and can serve as a biomarker for adverse cardiovascular outcomes in patients with chronic...
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Article
Open AccessRhabdomyolysis-induced acute kidney injury in a cancer patient exposed to denosumab and abiraterone: a case report
Denosumab and abiraterone were approved by the United States Food and Drug Administration in 2011 for the treatment of metastatic castration-resistant prostate cancer. Neither denosumab nor abiraterone is know...
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Article
Open AccessHemodialysis catheter insertion: is increased PO2 a sign of arterial cannulation? A case report
Ultrasound-guided Central Venous Catheterization (CVC) for temporary vascular access, preferably using the right internal jugular vein, is widely accepted by nephrologists. However CVC is associated with numer...
