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  1. Article

    Open Access

    KEA-1010, a ketamine ester analogue, retains analgesic and sedative potency but is devoid of Psychomimetic effects

    Ketamine, a widely used anaesthetic and analgesic agent, is known to improve the analgesic efficacy of opioids and to attenuate central sensitisation and opioid-induced hyperalgesia. Clinical use is, however, ...

    Martyn Harvey, Jamie Sleigh, Logan Voss, Mike Bickerdike… in BMC Pharmacology and Toxicology (2019)

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  2. No Access

    Article

    LIPAEMIC Report: Results of Clinical Use of Intravenous Lipid Emulsion in Drug Toxicity Reported to an Online Lipid Registry

    The use of intravenous lipid emulsion (ILE) as an antidote has prompted significant academic and clinical interest. Between August 2009 and August 2012, data from cases of ILE use in intoxicated patients in di...

    Grant Cave, Martyn Harvey, Johann Willers, David Uncles… in Journal of Medical Toxicology (2014)

  3. Article

    Open Access

    Case report: successful lipid resuscitation in multi-drug overdose with predominant tricyclic antidepressant toxidrome

    We report a case of profound neurologic and cardiovascular manifestations of tricyclic antidepressant intoxication following self-poisoning with multiple pharmaceuticals including amitriptyline in excess of 43...

    Martyn Harvey, Grant Cave in International Journal of Emergency Medicine (2012)

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  4. Article

    Intravenous Lipid Emulsion Does Not Augment Blood Pressure Recovery in A Rabbit Model of Metoprolol Toxicity

    Intravenous lipid emulsion (ILE) has been demonstrated to be an effective treatment for systemic toxicity associated with local anaesthetics and increasingly non-local anaesthetic agents of high lipophilicity. Ef...

    Alexander Browne, Martyn Harvey, Grant Cave in Journal of Medical Toxicology (2010)

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  5. Article

    Lipid emulsion may augment early blood pressure recovery in a rabbit model of atenolol toxicity

    Grant Cave, Martyn Harvey in Journal of Medical Toxicology (2009)

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