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Reference Work Entry In depth
Phase Transitions, Neural Population Models and
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Reference Work Entry In depth
Anesthesia, Neural Population Models of
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Reference Work Entry In depth
Gap Junctions, Neural Population Models and
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Article
Monitoring the level of hypnosis using a hierarchical SVM system
Monitoring level of hypnosis is a major ongoing challenge for anesthetists to reduce anesthetic drug consumption, avoiding intraoperative awareness and prolonged recovery. This paper proposes a novel automated...
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Article
Open AccessKEA-1010, a ketamine ester analogue, retains analgesic and sedative potency but is devoid of Psychomimetic effects
Ketamine, a widely used anaesthetic and analgesic agent, is known to improve the analgesic efficacy of opioids and to attenuate central sensitisation and opioid-induced hyperalgesia. Clinical use is, however, ...
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Article
Frontal–temporal functional connectivity of EEG signal by standardized permutation mutual information during anesthesia
Quantifying brain dynamics during anesthesia is an important challenge for understanding the neurophysiological mechanisms of anesthetic drug effect. Several single channel Electroencephalogram (EEG) indices h...
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Article
Open AccessModulation of frontal EEG alpha oscillations during maintenance and emergence phases of general anaesthesia to improve early neurocognitive recovery in older patients: protocol for a randomised controlled trial
Postoperative delirium may manifest in the immediate post-anaesthesia care period. Such episodes appear to be predictive of further episodes of inpatient delirium and associated adverse outcomes. Frontal elect...
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Article
Comparison of local spectral modulation, and temporal correlation, of simultaneously recorded EEG/fMRI signals during ketamine and midazolam sedation
The identification of biomarkers of drug action can be supported by non-invasive brain imaging techniques, such as electroencephalography (EEG) and functional magnetic resonance imaging (fMRI), with simultaneo...
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Article
Optimal Model Parameter Estimation from EEG Power Spectrum Features Observed during General Anesthesia
Mathematical modeling is a powerful tool that enables researchers to describe the experimentally observed dynamics of complex systems. Starting with a robust model including model parameters, it is necessary t...
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Article
Open AccessThalamo-cortical mechanisms of the observed specific changes in frontal and occipital EEG rhythms during propofol-induce sedation
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Article
How the cortico-thalamic feedback affects the EEG power spectrum over frontal and occipital regions during propofol-induced sedation
Increasing concentrations of the anaesthetic agent propofol initially induces sedation before achieving full general anaesthesia. During this state of anaesthesia, the observed specific changes in electroencep...
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Reference Work Entry In depth
Phase Transitions, Neural Population Models and
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Reference Work Entry In depth
Anesthesia, Neural Population Models of
-
Reference Work Entry In depth
Gap Junctions, Neural Population Models and
-
Article
Open AccessReproduction of EEG power spectrum over frontal region during the propofol-induced general anesthesia
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Article
Open AccessWhat can be learned from high-resolution sleep data using ECoG
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Article
Open AccessInterpretation of seizure evolution pathways via a mean-field cortical model
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Chapter
Anesthesia-Induced State Transitions in Neuronal Populations
It is a simple observation that the function of the central nervous system changes abruptly at certain critical brain concentrations of the anesthetic drug. This can be viewed as analogous to “state transition...
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Article
Open AccessDense gap-junction connections support dynamic Turing structures in the cortex