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  1. No Access

    Article

    Relationships of alcohol dehydrogenase 1B (ADH1B) and aldehyde dehydrogenase 2 (ALDH2) genotypes with alcohol sensitivity, drinking behavior and problem drinking in Japanese older men

    Many East Asians have the genetic polymorphisms rs1229984 in alcohol dehydrogenase 1B (ADH1B) and rs671 in aldehyde dehydrogenase 2 (ALDH2). Here we analyzed the relationships of the two genotypes with alcohol se...

    Marowa Hashimoto, Masutaka Watanabe… in Environmental Health and Preventive Medici… (2016)

  2. No Access

    Article

    Direct Detection of Single Nucleotide Polymorphism (SNP) by the TaqMan PCR Assay Using Dried Saliva on Water-soluble Paper and Hair-roots, without DNA Extraction

    We have developed a new method for directly using unprocessed biological specimens as templates for the TaqMan assay. DNA extraction and purification had been believed to be required for the assay, but our new...

    Mariko Hayashida, Tomoko Ota, Minori Ishii, Kyoko Iwao-Koizumi… in Analytical Sciences (2014)

  3. No Access

    Article

    Genoty** of Polymorphisms in Alcohol and Aldehyde Dehydrogenase Genes by Direct Application of PCR-RFLP on Dried Blood without DNA Extraction

    We have developed a simple, labor-saving, inexpensive, and rapid single nucleotide polymorphism (SNP) genoty** method that works directly on whole human blood. This single-tube genoty** method was used to ...

    Mariko Hayashida, Kyoko Iwao-Koizumi, Shigenori Murata… in Analytical Sciences (2010)

  4. No Access

    Article

    Single-Tube Genoty** from a Human Hair Root by Direct PCR

    We have developed a simple, labor-saving, inexpensive and rapid SNP genoty** method that directly uses a human hair root as the template. This single-tube genoty** method was used to successfully and relia...

    Mariko Hayashida, Kyoko Iwao-Koizumi, Shigenori Murata… in Analytical Sciences (2009)