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  1. Article

    Open Access

    Comparison of the inhibitory effect of tocilizumab and etanercept on the progression of joint erosion in rheumatoid arthritis treatment

    We compared the efficacy of tocilizumab and etanercept in inhibiting radiographic progression of joint destruction in rheumatoid arthritis. Overall, 187 patients treated with etanercept or tocilizumab were sel...

    Shinya Hayashi, Tsukasa Matsubara, Toshihisa Maeda, Koji Fukuda… in Scientific Reports (2022)

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  2. Article

    Open Access

    Predictive factors for effective selection of Interleukin-6 inhibitor and tumor necrosis factor inhibitor in the treatment of rheumatoid arthritis

    Treatment of rheumatoid arthritis (RA) is aimed at long-term remission and inhibition of joint destruction by different biologic drugs. However, the choice of a particular biologic agent based on individual ca...

    Shinya Hayashi, Tsukasa Matsubara, Koji Fukuda, Keiko Funahashi… in Scientific Reports (2020)

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  3. No Access

    Article

    Age and gender differences in the influences of eNOS T-786C polymorphism on arteriosclerotic parameters in general population in Japan

    The influence of T-786C polymorphism in the promoter region of endothelial nitric oxide synthase (eNOS) on arteriosclerotic parameters by age and gender were examined.

    Marowa Hashimoto, Nobuyuki Miyai… in Environmental Health and Preventive Medici… (2016)

  4. No Access

    Article

    Relationships of alcohol dehydrogenase 1B (ADH1B) and aldehyde dehydrogenase 2 (ALDH2) genotypes with alcohol sensitivity, drinking behavior and problem drinking in Japanese older men

    Many East Asians have the genetic polymorphisms rs1229984 in alcohol dehydrogenase 1B (ADH1B) and rs671 in aldehyde dehydrogenase 2 (ALDH2). Here we analyzed the relationships of the two genotypes with alcohol se...

    Marowa Hashimoto, Masutaka Watanabe… in Environmental Health and Preventive Medici… (2016)

  5. No Access

    Chapter

    Extreme Contrast of Postprandial Remnant-Like Particles Formed in Abetalipoproteinemia and Homozygous Familial Hypobetalipoproteinemia

    Background: Familial hypobetalipoproteinemia (FHBL) and abetalipoproteinemia (ABL) are rare inherited forms of hypolipidemia. Their differential diagnosis is important for predicting of the prognos...

    Masa-aki Kawashiri, Hayato Tada, Marowa Hashimoto… in JIMD Reports, Volume 22 (2015)