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  1. Article

    Open Access

    Modeling gene-environment interactions in longitudinal family studies: a comparison of methods and their application to the association between the IGF pathway and childhood obesity

    The interactive effect of the IGF pathway genes with the environment may contribute to childhood obesity. Such gene-environment interactions can take on complex forms. Detecting those relationships using longi...

    Cheng Wang, Marie-Hélène Roy-Gagnon, Jean-François Lefebvre in BMC Medical Genetics (2019)

  2. Article

    Open Access

    The association between the angiotensin-converting enzyme-2 gene and blood pressure in a cohort study of adolescents

    The Angiotensin-Converting Enzyme-2 (ACE2) gene, located on chromosome X, is believed to be implicated in blood pressure regulation. However the few studies that have examined this association have yielded mix...

    Lucile Malard, Lisa Kakinami, Jennifer O’Loughlin in BMC Medical Genetics (2013)

  3. No Access

    Article

    Genomic and genealogical investigation of the French Canadian founder population structure

    Characterizing the genetic structure of worldwide populations is important for understanding human history and is essential to the design and analysis of genetic epidemiological studies. In this study, we exam...

    Marie-Hélène Roy-Gagnon, Claudia Moreau, Claude Bherer, Pascal St-Onge in Human Genetics (2011)