13 Result(s)
within
Marie-Hélène Roy-Gagnon
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Article
Open AccessThe impact of fast food marketing on brand preferences and fast food intake of youth aged 10–17 across six countries
Consumption of fast food, which is associated with poor diet, weight gain and the development of noncommunicable diseases, is high amongst youth. Fast food marketing, a modifiable determinant of excess weight ...
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Article
Open AccessComparison of mixed model based approaches for correcting for population substructure with application to extreme phenotype sampling
Mixed models are used to correct for confounding due to population stratification and hidden relatedness in genome-wide association studies. This class of models includes linear mixed models and generalized li...
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Article
General and abdominal obesity trajectories across adulthood, and risk of prostate cancer: results from the PROtEuS study, Montreal, Canada
Greater body fatness is a probable cause of advanced prostate cancer (PCa). Body fat distribution and timing of exposure may be relevant. We investigated associations between body size trajectories and PCa inc...
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Article
Open AccessUtilization of key preventive measures for pregnancy complications and malaria among women in Jimma Zone, Ethiopia
In Ethiopia, malaria infections and other complications during pregnancy contribute to the high burden of maternal morbidity and mortality. Preventive measures are available, however little is known about the ...
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Article
Open AccessModeling gene-environment interactions in longitudinal family studies: a comparison of methods and their application to the association between the IGF pathway and childhood obesity
The interactive effect of the IGF pathway genes with the environment may contribute to childhood obesity. Such gene-environment interactions can take on complex forms. Detecting those relationships using longi...
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Article
Open AccessFactors associated with human West Nile virus infection in Ontario: a generalized linear mixed modelling approach
West Nile Virus (WNV) is a mosquito-borne pathogen that has become established in North America. Risk for human infection varies geographically in accordance with climate and population factors. Though often a...
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Article
Open AccessAge-Related Eye Disease and Participation in Cognitive Activities
Studies have found a benefit to living a cognitively active life in older age. Our goal was to quantify participation in cognitively stimulating activities in adults with and without age-related eye disease. W...
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Article
Open AccessGENLIB: an R package for the analysis of genealogical data
Founder populations have an important role in the study of genetic diseases. Access to detailed genealogical records is often one of their advantages. These genealogical data provide unique information for res...
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Article
Open AccessIdentifying risk profiles for childhood obesity using recursive partitioning based on individual, familial, and neighborhood environment factors
Few studies consider how risk factors within multiple levels of influence operate synergistically to determine childhood obesity. We used recursive partitioning analysis to identify unique combinations of indi...
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Article
Open AccessThe association between the angiotensin-converting enzyme-2 gene and blood pressure in a cohort study of adolescents
The Angiotensin-Converting Enzyme-2 (ACE2) gene, located on chromosome X, is believed to be implicated in blood pressure regulation. However the few studies that have examined this association have yielded mix...
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Article
Genomic and genealogical investigation of the French Canadian founder population structure
Characterizing the genetic structure of worldwide populations is important for understanding human history and is essential to the design and analysis of genetic epidemiological studies. In this study, we exam...
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Article
Open AccessApplication of the regression of offspring on mid-parent method to detect associations between single-nucleotide polymorphisms and the beta 2 electroencephalogram phenotype in the COGA data
The beta 2 electroencephalogram (EEG) phenotype is used as a quantitative measure related to alcoholism, and evidence of linkage and association has previously been reported in the Collaborative Study on the G...
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Article
Open AccessComparison of year-of-exam- and age-matched estimates of heritability in the Framingham Heart Study data
Several different approaches can be used to examine generational and temporal trends in family studies. The measurement of offspring and parents can be made over a short period of time with parents and offspri...
