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Article
Open AccessMixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling
The phenomenon of mixed/heterogenous treatment responses to cancer therapies within an individual patient presents a challenging clinical scenario. Furthermore, the molecular basis of mixed intra-patient tumor...
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Article
Publisher Correction: A clonal expression biomarker associates with lung cancer mortality
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Open AccessThe Role of TRAF4 and B3GAT1 Gene Expression in the Food Hypersensitivity and Insect Venom Allergy in Mastocytosis
Mastocytosis is an uncommon disease classified as a myeloproliferative neoplasm, however, its symptoms are broad and place patients at crossroads between dermatology, hematology and allergology. Patients with ...
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Article
Open AccessPrognostic value of 5-microRNA based signature in T2-T3N0 colon cancer
The role of adjuvant chemotherapy in stage T2-T3N0 colon cancer (CC) is controversial and there are currently no reliable factors allowing for individual selection of patients with high risk of relapse for suc...
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Article
Open AccessCombined clinical and genomic signatures for the prognosis of early stage non-small cell lung cancer based on gene copy number alterations
The development of a more refined prognostic methodology for early non-small cell lung cancer (NSCLC) is an unmet clinical need. An accurate prognostic tool might help to select patients at early stages for ad...