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Article
Open AccessONECUT2 is a druggable driver of luminal to basal breast cancer plasticity
Tumor heterogeneity complicates patient treatment and can be due to transitioning of cancer cells across phenotypic cell states. This process is associated with the acquisition of independence from an oncogeni...
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Article
Open AccessErratum to: Telomere shortening and accelerated aging in COPD: findings from the BODE cohort
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Article
Open AccessTelomere shortening and accelerated aging in COPD: findings from the BODE cohort
Chronic Obstructive Pulmonary Disease (COPD) may be associated with accelerated aging. Telomere shortening is a biomarker of aging. Cross-sectional studies describe shorter telomeres in COPD compared with matc...
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Article
Open AccessCombined clinical and genomic signatures for the prognosis of early stage non-small cell lung cancer based on gene copy number alterations
The development of a more refined prognostic methodology for early non-small cell lung cancer (NSCLC) is an unmet clinical need. An accurate prognostic tool might help to select patients at early stages for ad...
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Article
Open AccessTGFBI expression is associated with a better response to chemotherapy in NSCLC
Lung cancer is one of the most prevalent neoplasias in developed countries. Advances in patient survival have been limited and the identification of prognostic molecules is needed. Resistance to treatment is s...