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  1. No Access

    Article

    Chiral separation of aminoalcohols by ion-pair chromatography

    A new chiral counter ion, N-benzoxycarbonyl-glycyl-L-proline (ZGP), added to the organic mobile phase (dichloromethane) has been used for separation of enantiomers of aminoalcohols with LiChrosorb DIOL as the ...

    C. Pettersson, M. Josefsson in Chromatographia (1986)

  2. No Access

    Article

    Fast chromatographic separation of (−)-menthyl chloroformate derivatives of some chiral drugs, with special reference to amlodipine, on porous graphitic carbon

    Enantiomeric separation of (−)-menthyl chloroformate derivatives of some chiral cardioactive drugs, on porous graphitic carbon (PGC), Hypercarb-S, is described. Capacity and separation factors of derivatives o...

    M. Josefsson, B. Carlsson, B. Norlander in Chromatographia (1993)

  3. No Access

    Article

    Effect of grapefruit juice on the pharmacokinetics of amlodipine in healthy volunteers

    Objective: This study was performed to assess whether coadminstration with grapefruit juice significantly affects the pharmacokinetics of amlodipine, a dihydropyridine class calcium anta...

    M. Josefsson, A.-L. Zackrisson, J. Ahlner in European Journal of Clinical Pharmacology (1996)

  4. No Access

    Article

    Influence of CYP2D6 and CYP2C19 genotypes on venlafaxine metabolic ratios and stereoselective metabolism in forensic autopsy cases

    We investigated whether polymorphisms in the CYP2D6 and CYP2C19 genes influence the metabolic ratios and enantiomeric S/R ratios of venlafaxine (VEN) and its metabolites O-desmethylvenlafaxine (ODV), N-desmethylv...

    L Karlsson, A-L Zackrisson, M Josefsson, B Carlsson… in The Pharmacogenomics Journal (2015)