13 Result(s)

Article

Clinical need for bone morphogenetic proteins

Slobodan Vukičević, Lovorka Grgurević, Marko Pećina in International Orthopaedics (2017)

Article

Biological aspects of segmental bone defects management

Segmental bone defect management is among the most demanding issues in orthopaedics and there is a great medical need for establishing an appropriate treatment option. Tissue transfer, including bone autograft...

Ivo Dumic-Cule, Marko Pecina, Mislav Jelic, Morana Jankolija… in International Orthopaedics (2015)

Article

Exogenous BMP7 corrects plasma iron overload and bone loss in Bmp6-/- mice

Iron overload accelerates bone loss in mice lacking the bone morphogenetic protein 6 (Bmp6) gene, which is the key endogenous regulator of hepcidin, iron homeostasis gene. We investigated involvement of other BMP...

Martina Pauk, Lovorka Grgurevic, Jelena Brkljacic… in International Orthopaedics (2015)

Reference Work Entry In depth

Scaffold-Free Endogenous Healing of the Articular Cartilage Lesion

The regeneration of the joint cartilage remains a major challenge in medicine, because the factors initiating cartilage formation, maturation, and healing are poorly understood. The ideal outcome of the joint ...

Mislav Jelic, Lovorka Grgurevic, Slobodan Vukicevic in Sports Injuries (2015)

Article

Dynamics of optic canal and orbital cavity development revealed by microCT

Numerous studies have attempted to clarify the exact anatomy and variations of the optic canal with non-conclusive results due to its close proximity to many vulnerable structures. We sought to determine the d...

Ivo Dumic-Cule, Domagoj Eljuga, Ali Izadpanah… in Surgical and Radiologic Anatomy (2014)

Article

Systemically available bone morphogenetic protein two and seven affect bone metabolism

Bone morphogenetic protein (BMP)-2 and -7 are used in patients with long-bone fractures, nonunions and spinal fusions. It is unknown whether their potential systemic bioavailability following local bone admini...

Ivo Dumic-Cule, Jelena Brkljacic, Dunja Rogic… in International Orthopaedics (2014)

Article

The clinical use of bone morphogenetic proteins revisited: a novel biocompatible carrier device OSTEOGROW for bone healing

The purpose of this study was to revise the clinical use of commercial BMP2 (Infuse) and BMP7 (Osigraft) based bone devices and explore the mechanism of action and efficacy of low BMP6 doses in a novel whole b...

Slobodan Vukicevic, Hermann Oppermann, Donatella Verbanac… in International Orthopaedics (2014)

Living Reference Work Entry In depth

Scaffold-Free Endogenous Healing of the Articular Cartilage Lesion

The regeneration of the joint cartilage remains a major challenge in medicine, because the factors initiating cartilage formation, maturation, and healing are poorly understood. The ideal outcome of the joint ...

Mislav Jelic, Lovorka Grgurevic, Slobodan Vukicevic in Sports Injuries

Article

Exogenous heparin binds and inhibits bone morphogenetic protein 6 biological activity

The purpose of this study was to explore the effect of heparin on bone morphogenetic protein 6 (BMP6) osteogenic activity.

Jelena Brkljacic, Martina Pauk, Igor Erjavec, Antonio Cipcic… in International Orthopaedics (2013)

Chapter

Systemic administration of bone morphogenetic proteins

Apart from the local application, bone morphogenetic proteins (BMPs) have been systemically applied in rats for the following indications: bone formation in a model of osteoporosis [1], kidney regeneration in mod...

Slobodan Vukicevic, Petra Simic… in Bone Morphogenetic Proteins: From Local to… (2008)

Article

Detection of bone and cartilage-related proteins in plasma of patients with a bone fracture using liquid chromatography–mass spectrometry

Following bone fracture, a large number of growth factors, cytokines, and their cognate receptors involved in the repair process are active at the fracture site. To determine whether they appear in patients’ b...

Lovorka Grgurevic, Boris Macek, Dragan Durdevic… in International Orthopaedics (2007)