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  1. Article

    Open Access

    KEA-1010, a ketamine ester analogue, retains analgesic and sedative potency but is devoid of Psychomimetic effects

    Ketamine, a widely used anaesthetic and analgesic agent, is known to improve the analgesic efficacy of opioids and to attenuate central sensitisation and opioid-induced hyperalgesia. Clinical use is, however, ...

    Martyn Harvey, Jamie Sleigh, Logan Voss, Mike Bickerdike in BMC Pharmacology and Toxicology (2019)