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  1. Article

    Open Access

    Overcoming challenges in the economic evaluation of interventions to optimise antibiotic use

    Bacteria are becoming increasingly resistant to antibiotics, reducing our ability to treat infections and threatening to undermine modern health care. Optimising antibiotic use is a key element in tackling the...

    Laurence S. J. Roope, Liz Morrell, James Buchanan, Alice Ledda in Communications Medicine (2024)

  2. Article

    Open Access

    What Aspects of Illness Influence Public Preferences for Healthcare Priority Setting? A Discrete Choice Experiment in the UK

    Decisions on funding new healthcare technologies assume that all health improvements are valued equally. However, public reaction to health technology assessment (HTA) decisions suggests there are health attri...

    Liz Morrell, James Buchanan, Sian Rees, Richard W. Barker in PharmacoEconomics (2021)

  3. Article

    Open Access

    Preferences for Medical Consultations from Online Providers: Evidence from a Discrete Choice Experiment in the United Kingdom

    In the UK, consultations for prescription medicines are available via private providers such as online pharmacies. However, these providers may have lower thresholds for prescribing certain drugs. This is a pa...

    James Buchanan, Laurence S. J. Roope in Applied Health Economics and Health Policy (2021)

  4. Article

    Open Access

    Why do hospital prescribers continue antibiotics when it is safe to stop? Results of a choice experiment survey

    Deciding whether to discontinue antibiotics at early review is a cornerstone of hospital antimicrobial stewardship practice worldwide. In England, this approach is described in government guidance (‘Start Smar...

    Laurence S. J. Roope, James Buchanan, Liz Morrell, Koen B. Pouwels in BMC Medicine (2020)

  5. Article

    Open Access

    Mind the gap? The platform trial as a working environment

    Trials have become bigger and more complicated due to the complexity introduced by biomarker stratification, and the advent of multi-arm multi-stage trials, and umbrella and basket platform designs. The trials...

    Liz Morrell, Joshua Hordern, Louise Brown, Matthew R. Sydes, Claire L. Amos in Trials (2019)

  6. Article

    Open Access

    Correction to: Will the reformed Cancer Drugs Fund address the most common types of uncertainty? An analysis of NICE cancer drug appraisals

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    Liz Morrell, Sarah Wordsworth, Anna Schuh in BMC Health Services Research (2019)

  7. Article

    Open Access

    Will the reformed Cancer Drugs Fund address the most common types of uncertainty? An analysis of NICE cancer drug appraisals

    One of the functions of the reformed Cancer Drugs Fund in England is as a managed access fund, providing conditional funding for cancer drugs where there is uncertainty in the economic case, and where that unc...

    Liz Morrell, Sarah Wordsworth, Anna Schuh in BMC Health Services Research (2018)

  8. Article

    Open Access

    Cancer drug funding decisions in Scotland: impact of new end-of-life, orphan and ultra-orphan processes

    The Scottish Medicines Consortium evaluates new drugs for use in the National Health Service in Scotland. Reforms in 2014 to their evaluation process aimed to increase patient access to new drugs for end-of-li...

    Liz Morrell, Sarah Wordsworth, Howell Fu, Sian Rees in BMC Health Services Research (2017)

  9. Article

    Open Access

    Does the Public Prefer Health Gain for Cancer Patients? A Systematic Review of Public Views on Cancer and its Characteristics

    Policies such as the Cancer Drugs Fund in England assumed a societal preference to fund cancer care relative to other conditions, even if that resulted in lower health gain for the population overall.

    Liz Morrell, Sarah Wordsworth, Sian Rees, Richard Barker in PharmacoEconomics (2017)