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  1. Article

    Open Access

    miR-29b-3p regulates cardiomyocytes pyroptosis in CVB3-induced myocarditis through targeting DNMT3A

    Viral myocarditis (VMC) is a disease resulting from viral infection, which manifests as inflammation of myocardial cells. Until now, the treatment of VMC is still a great challenge for clinicians. Increasing s...

    Ya Wang, Zhengyang Zhang, Hui Li, Min Wang in Cellular & Molecular Biology Letters (2024)

  2. No Access

    Article

    Selection and verification of reliable internal reference genes in stem development of herbaceous peony (Paeonia lactiflora Pall.)

    Herbaceous peony (Paeonia lactiflora Pall.) has emerged in the cut flower market due to its beautiful appearance. The bending flower stems caused by a lack of mechanical strength is the main problem restricting t...

    Lili Lu, Yuhan Tang, Huajie Xu, Yi Qian in Physiology and Molecular Biology of Plants (2023)

  3. No Access

    Article

    The cotton protein GhIQD21 interacts with GhCaM7 and modulates organ morphogenesis in Arabidopsis by influencing microtubule stability

    GhIQD21, a cotton IQ67-domain protein, interacts with GhCaM7 and alters organ shape in Arabidopsis by modulating microtubule stability.

    **ng Li, Li Wang, Yupeng Cui, Chen Liu, Yujie Liu, Lili Lu, Ming Luo in Plant Cell Reports (2023)

  4. No Access

    Article

    GhBES1 mediates brassinosteroid regulation of leaf size by activating expression of GhEXO2 in cotton (Gossypium hirsutum)

    We proposed a working model of BR to promote leaf size through cell expansion. In the BR signaling pathway, GhBES1 affects cotton leaf size by binding to and activating the expression of the E-box element in the

    Shengdong Li, Kun **ng, Ghulam Qanmber, Guoquan Chen, Le Liu in Plant Molecular Biology (2023)

  5. No Access

    Article

    Identification and Characterization of miRNAs and Their Predicted mRNAs in the Larval Development of Pearl Oyster Pinctada fucata

    As an important economic shellfish, the pearl oyster, Pinctada fucata, and its larvae are an ideal model for studying molecular mechanisms of larval development in invertebrates. Larval development directly affec...

    Jian Chen, Ziqin Zhai, Lili Lu, Su** Li, Dan Guo, Lirong Bai in Marine Biotechnology (2022)

  6. No Access

    Article

    Identification of BR biosynthesis genes in cotton reveals that GhCPD-3 restores BR biosynthesis and mediates plant growth and development

    Brassinosteroid (BR) synthesis genes in different cotton species was comprehensively identified, and the participation of GhCPD-3 in the BR synthesis signaling pathway for regulating plant development was verifie...

    Le Liu, Zongming **e, Lili Lu, Ghulam Qanmber, Guoquan Chen, Shengdong Li in Planta (2021)

  7. No Access

    Article

    Sodium P-aminosalicylic Acid Inhibits Manganese-Induced Neuroinflammation in BV2 Microglial Cells via NLRP3-CASP1 Inflammasome Pathway

    Sodium p-aminosalicylic acid (PAS-Na) was reported to exhibit anti-inflammatory effect in the nervous system. However, the mechanism by which PAS-Na exhibits anti-inflammatory effects on manganese (Mn)-stimula...

    Yuanyuan Fang, Dongjie Peng, Yuan Liang, Lili Lu in Biological Trace Element Research (2021)

  8. No Access

    Article

    Metabolic scaling: individual versus intraspecific scaling of Nile tilapia (Oreochromis niloticus)

    We examined intraspecific scaling of the resting metabolic rate (RMR) of Nile tilapia (Oreochromis niloticus) under different culture conditions and further explored the allometric relationships between organ mas...

    **urong Ye, Lili Lu, Meijun Jiang, Jiuman Jia in Journal of Comparative Physiology B (2021)

  9. No Access

    Article

    Converting a β-N-acetylhexosaminidase into two trans-β-N-acetylhexosaminidases by domain-targeted mutagenesis

    We have recently derived a β-N-acetylhexosaminidase, BbhI, from Bifidobacterium bifidum JCM 1254, which could regioselectively synthesize GlcNAcβ1-3Galβ1-4Glc with a yield of 44.9%. Here, directed evolution of Bb...

    **aodi Chen, Lan **, Xukai Jiang, Longcheng Guo in Applied Microbiology and Biotechnology (2020)

  10. No Access

    Article

    Enzymatic rhamnosylation of anticancer drugs by an α-l-rhamnosidase from Alternaria sp. L1 for cancer-targeting and enzyme-activated prodrug therapy

    The synthesis of rhamnosylated compounds has gained great importance since these compounds have potential therapeutic applications. The enzymatic approaches for glycosylation of bioactive molecules have been w...

    Li Xu, **aohong Liu, Yin** Li, Zhenhao Yin in Applied Microbiology and Biotechnology (2019)

  11. Article

    Open Access

    Genome-wide identification of Gossypium INDETERMINATE DOMAIN genes and their expression profiles in ovule development and abiotic stress responses

    INDETERMINATE DOMAIN (IDD) transcription factors form one of the largest and most conserved gene families in plant kingdom and play important roles in various processes of plant growth and development, such as fl...

    Faiza ALI, Ghulam QANMBER, Yonghui LI, Shuya MA, Lili LU in Journal of Cotton Research (2019)

  12. No Access

    Article

    GhKLCR1, a kinesin light chain-related gene, induces drought-stress sensitivity in Arabidopsis

    Drought stress results in significant losses in agricultural production, and especially that of cotton. The molecular mechanisms that coordinate drought tolerance remain elusive in cotton. Here, we isolated a ...

    Jie Li, Daoqian Yu, Ghulam Qanmber, Lili Lu, Lingling Wang in Science China Life Sciences (2019)

  13. Article

    Open Access

    Genome-wide analysis of cotton GH3 subfamily II reveals functional divergence in fiber development, hormone response and plant architecture

    Auxin-induced genes regulate many aspects of plant growth and development. The Gretchen Hagen 3 (GH3) gene family, one of three major early auxin-responsive families, is ubiquitous in the plant kingdom and its me...

    Daoqian Yu, Ghulam Qanmber, Lili Lu, Lingling Wang, Jie Li in BMC Plant Biology (2018)

  14. Article

    Open Access

    Genome-wide characterization and phylogenetic analysis of GSK gene family in three species of cotton: evidence for a role of some GSKs in fiber development and responses to stress

    The glycogen synthase kinase 3/shaggy kinase (GSK3) is a serine/threonine kinase with important roles in animals. Although GSK3 genes have been studied for more than 30 years, plant GSK genes have been studied on...

    Lingling Wang, Zhaoen Yang, Bin Zhang, Daoqian Yu, Ji Liu, Qian Gong in BMC Plant Biology (2018)

  15. No Access

    Article

    Genome-wide analysis of BES1 genes in Gossypium revealed their evolutionary conserved roles in brassinosteroid signaling

    Brassinosteroids (BRs), which are essential phytohormones for plant growth and development, are important for cotton fiber development. Additionally, BES1 transcription factors are critical for BR signal transduc...

    Zhao Liu, Ghulam Qanmber, Lili Lu, Wenqiang Qin, Ji Liu in Science China Life Sciences (2018)

  16. Article

    Open Access

    Genome-wide identification and expression analysis of Gossypium RING-H2 finger E3 ligase genes revealed their roles in fiber development, and phytohormone and abiotic stress responses

    RING-H2 finger E3 ligase (RH2FE3) genes encode cysteine-rich proteins that mediate E3 ubiquitin ligase activity and degrade target substrates. The roles of these genes in plant responses to phytohormones and a...

    Ghulam QANMBER, Daoqian YU, Jie LI, Lingling WANG, Shuya MA in Journal of Cotton Research (2018)

  17. No Access

    Article

    Rational designed mutagenesis of levansucrase from Bacillus licheniformis 8-37-0-1 for product specificity study

    Levansucrases, which belong to the glycoside hydrolase family 68 (GH68), synthesize β (2-6)-linked fructan levan with sucrose as substrate. We described the use of a levansucrase (Bl_SacB) from Bacillus lichenifo...

    Chunjuan He, Yirui Yang, Renfei Zhao, **gyao Qu in Applied Microbiology and Biotechnology (2018)

  18. Article

    Open Access

    Genome-wide analysis of WOX genes in upland cotton and their expression pattern under different stresses

    WUSCHEL-related homeobox (WOX) family members play significant roles in plant growth and development, such as in embryo patterning, stem-cell maintenance, and lateral organ formation. The recently published co...

    Zhaoen Yang, Qian Gong, Wenqiang Qin, Zuoren Yang, Yuan Cheng, Lili Lu in BMC Plant Biology (2017)

  19. No Access

    Article

    Efficient synthesis of tyrosol galactosides by the β-galactosidase from Enterobacter cloacae B5

    In this work, the β-galactosidase from Enterobacter cloacae B5 (BgaB5) exhibited excellent transglycosylation activity toward tyrosol (p-hydroxyphenethyl alcohol) when using lactose as the glycosyl donor, generat...

    Tingting Qi, Guofeng Gu, Li Xu, Min **ao, Lili Lu in Applied Microbiology and Biotechnology (2017)

  20. No Access

    Article

    Site-directed mutagenesis of α-l-rhamnosidase from Alternaria sp. L1 to enhance synthesis yield of reverse hydrolysis based on rational design

    The α-l-rhamnosidase catalyzes the hydrolytic release of rhamnose from polysaccharides and glycosides and is widely used due to its applications in a variety of industrial processes. Our previous work reported th...

    Li Xu, **aohong Liu, Zhenhao Yin, Qian Liu in Applied Microbiology and Biotechnology (2016)

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