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  1. No Access

    Article

    Enzymatic rhamnosylation of anticancer drugs by an α-l-rhamnosidase from Alternaria sp. L1 for cancer-targeting and enzyme-activated prodrug therapy

    The synthesis of rhamnosylated compounds has gained great importance since these compounds have potential therapeutic applications. The enzymatic approaches for glycosylation of bioactive molecules have been w...

    Li Xu, **aohong Liu, Yin** Li, Zhenhao Yin… in Applied Microbiology and Biotechnology (2019)

  2. No Access

    Article

    Site-directed mutagenesis of α-l-rhamnosidase from Alternaria sp. L1 to enhance synthesis yield of reverse hydrolysis based on rational design

    The α-l-rhamnosidase catalyzes the hydrolytic release of rhamnose from polysaccharides and glycosides and is widely used due to its applications in a variety of industrial processes. Our previous work reported th...

    Li Xu, **aohong Liu, Zhenhao Yin, Qian Liu… in Applied Microbiology and Biotechnology (2016)

  3. No Access

    Article

    Fermentation of ginseng extracts by Penicillium simplicissimum GS33 and anti-ovarian cancer activity of fermented products

    A total of 58 isolates of β-glucosidase-producing microorganisms were isolated from soil around the wild ginseng roots under forest using Esculin-R2A agar. Among these isolates, strain GS33 showed a strong abi...

    Yu Fu, Zhenhao Yin, Lunpeng Wu, Chengri Yin in World Journal of Microbiology and Biotechn… (2014)