-
Article
Open AccessExploring women’s interpretations of survey questions on pregnancy and pregnancy outcomes: cognitive interviews in Iganga Mayuge, Uganda
In 2021, Uganda’s neonatal mortality rate was approximately 19 deaths per 1000 live births, with an estimated stillbirth rate of 15.1 per 1000 total births. Data are critical for indicating areas where deaths ...
-
Article
Open AccessPsychosocial effects of adverse pregnancy outcomes and their influence on reporting pregnancy loss during surveys and surveillance: narratives from Uganda
In 2021, Uganda had an estimated 25,855 stillbirths and 32,037 newborn deaths. Many Adverse Pregnancy Outcomes (APOs) go unreported despite causing profound grief and other mental health effects. This study ex...
-
Article
Open AccessA facilitated social innovation: stakeholder groups using Plan-Do-Study-Act cycles for perinatal health across levels of the health system in Cao Bang province, Vietnam
Universal coverage of evidence-based interventions for perinatal health, often part of evidence-based guidelines, could prevent most perinatal deaths, particularly if entire communities were engaged in the imp...
-
Article
Open AccessTraining and support for the role of facilitator in implementation of innovations in health and community care: a sco** review protocol
Implementing and sustaining innovations in clinical practice, such as evidence-based practices, programmes, and policies, is frequently described as challenging. Facilitation as a strategy for supporting imple...
-
Article
Open AccessAdverse pregnancy outcome disclosure and women’s social networks: a qualitative multi-country study with implications for improved reporting in surveys
Globally, approximately 6,700 newborn deaths and 5,400 stillbirths occur daily. The true figure is likely higher, with under reporting of adverse pregnancy outcomes (APOs) noted. Decision-making in health is i...
-
Article
Open AccessBuilding implementation capacity in health care and welfare through team training—study protocol of a longitudinal mixed-methods evaluation of the building implementation capacity intervention
To ensure the provision of high-quality safety and cost-effective health and welfare services, managers and professionals are required to introduce and ensure the routine use of clinical guidelines and other e...
-
Article
Open AccessAlignment in implementation of evidence-based interventions: a sco** review
Alignment (i.e., the process of creating fit between elements of the inner and outer context of an organization or system) in conjunction with implementation of an evidence-based intervention (EBI) has been id...
-
Article
Open AccessHealthcare professionals’ perceptions about interprofessional teamwork: a national survey within Swedish child healthcare services
Globally, interprofessional teamwork is described as a key method to promote health and prevent illness in children, namely, to achieve the goals of Child Healthcare Services (CHS). However, how teamwork shoul...
-
Article
Open AccessLife situation and support during pregnancy among Thai expectant mothers with depressive symptoms and their partners: a qualitative study
Expectant parents may have positive and negative emotions during pregnancy and receive support from different sources. Studies on life situation and support among couples have rarely been conducted. This study...
-
Article
Open AccessIntervention intended to improve public health professionals’ self-efficacy in their efforts to detect and manage perinatal depressive symptoms among Thai women: a mixed-methods study
Targeting perinatal depressive symptoms among women can reduce premature mortality. However, public health professionals (PHPs) in primary healthcare settings often have low self-efficacy for detection and man...
-
Article
Open AccessEffects of the Toll-like receptor 7 (TLR7) agonist, AZD8848, on allergen-induced responses in patients with mild asthma: a double-blind, randomised, parallel-group study
Although allergic asthma is a complex area with many interacting factors involved, the ‘hygiene hypothesis’ proposes that a lack of exposure to infection during childhood may polarise the immune system towards...
-
Article
Open AccessQuantifying extracellular matrix turnover in human lung scaffold cultures
Remodelling of the extracellular matrix is accomplished by altering the balance between matrix macromolecule production and degradation. However, it is not well understood how cells balance production of new m...
-
Article
Open AccessMSC from fetal and adult lungs possess lung-specific properties compared to bone marrow-derived MSC
Mesenchymal stromal cells (MSC) are multipotent cells with regenerative and immune-modulatory properties. Therefore, MSC have been proposed as a potential cell-therapy for bronchiolitis obliterans syndrome (BO...
-
Article
Open AccessProcess evaluation of a knowledge translation intervention using facilitation of local stakeholder groups to improve neonatal survival in the Quang Ninh province, Vietnam
Annually, 2.8 million neonatal deaths occur worldwide, despite the fact that three-quarters of them could be prevented if available evidence-based interventions were used. Facilitation of community groups has ...
-
Article
Open AccessExploring the influence of context in a community-based facilitation intervention focusing on neonatal health and survival in Vietnam: a qualitative study
In the Neonatal health – Knowledge into Practice (NeoKIP) trial in Vietnam, local stakeholder groups, supported by trained laywomen acting as facilitators, promoted knowledge translation (KT) resulting in decr...
-
Article
Open AccessEffect of facilitation of local maternal-and-newborn stakeholder groups on neonatal mortality: a cluster randomised trial
-
Article
Open AccessComparing progress toward the millennium development goal for under-five mortality in León and Cuatro Santos, Nicaragua, 1990–2008
Social inequality in child survival hampers the achievement of Millennium Development Goal 4 (MDG4). Monitoring under-five mortality in different social strata may contribute to public health policies that str...
-
Article
Open AccessLessons learned from stakeholders in a facilitation intervention targeting neonatal health in Quang Ninh province, Vietnam
In northern Vietnam the Neonatal health - Knowledge Into Practice (NeoKIP, Current Controlled Trials ISRCTN44599712) trial has evaluated facilitation as a knowledge translation intervention to improve neonatal...
-
Article
Open AccessEnhanced ROCK1 dependent contractility in fibroblast from chronic obstructive pulmonary disease patients
During wound healing processes fibroblasts account for wound closure by adopting a contractile phenotype. One disease manifestation of COPD is emphysema which is characterized by destruction of alveolar walls ...
-
Article
Open AccessRepeated intranasal TLR7 stimulation reduces allergen responsiveness in allergic rhinitis
Interactions between Th1 and Th2 immune responses are of importance to the onset and development of allergic disorders. A Toll-like receptor 7 agonist such as AZD8848 may have potential as a treatment for alle...
