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Article
Open AccessCost-effectiveness analysis of (accelerated) pre-operative versus (conventional) post-operative radiotherapy for patients with oral cavity cancer in Sweden
Treatment for resectable oral cavity cancer (OCC) often includes combinations of surgery and radiotherapy (RT), but there is no conclusive information on the preferred treatment order. The aim of this study wa...
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Article
Open AccessPredictors of survival in advanced oral cancers after salvage surgery with free tissue flap reconstruction
To identify prognostic factors for patients with advanced persistent, recurrent, or 2nd primary oral cavity squamous cell carcinoma (OCSCC) potentially unsuitable for salvage surgery with free tissue flap (FTF...
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Article
Open AccessCorrection to: Outcome for sinonasal malignancies: a population-based survey
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Article
Open AccessOutcome for sinonasal malignancies: a population-based survey
Sinonasal malignancies (SNM) represent a rare and complex group of cancers that includes a wide range of histopathological subtypes. Data from population-based cohorts are scarce but warranted as a basis for r...
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Article
Open AccessIntralesional EBV-DNA load as marker of prognosis for nasopharyngeal cancer
Nasopharyngeal cancer (NPC) is associated with the Epstein-Barr virus (EBV). The clinical presentation and prognosis of NPC is well described, but not in relation to intralesional EBV-DNA load. In a retrospect...
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Article
Open AccessProfiling dendritic cell subsets in head and neck squamous cell tonsillar cancer and benign tonsils
Dendritic cells (DCs) have a key role in orchestrating immune responses and are considered important targets for immunotherapy against cancer. In order to develop effective cancer vaccines, detailed knowledge ...
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Article
Open Access31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one
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Article
Open Access31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two
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Article
Biological effects and clinical efficacy of a topical Toll-like receptor 7 agonist in seasonal allergic rhinitis: a parallel group controlled phase IIa study
The purpose of the study was to examine effects of pre-treatment with a Toll-like receptor 7 (TLR7) agonist (AZD8848) in allergic rhinitis and to evaluate clinical effects of two dosing regimens.
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Article
Open AccessRepeated intranasal TLR7 stimulation reduces allergen responsiveness in allergic rhinitis
Interactions between Th1 and Th2 immune responses are of importance to the onset and development of allergic disorders. A Toll-like receptor 7 agonist such as AZD8848 may have potential as a treatment for alle...
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Article
Open AccessEarly phase resolution of mucosal eosinophilic inflammation in allergic rhinitis
It is widely assumed that apoptosis of eosinophils is a central component of resolution of allergic airway disease. However, this has not been demonstrated in human allergic airways in vivo. Based on animal in...
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Article
Open AccessEffects of a dual CCR3 and H1-antagonist on symptoms and eosinophilic inflammation in allergic rhinitis
The CC-chemokine receptor-3 (CCR3) has emerged as a target molecule for pharmacological intervention in allergic inflammation.
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Article
Open AccessEffects of intranasal TNFα on granulocyte recruitment and activity in healthy subjects and patients with allergic rhinitis
TNFα may contribute to the pathophysiology of airway inflammation. For example, we have recently shown that nasal administration of TNFα produces late phase co-appearance of granulocyte and plasma exudation ma...
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Protocol
Nasal Secretions and Exudations
Nasal and bronchoalveolar lavage techniques, as well as sputum inductiontechniques, are frequently used for sampling of airway mucosal surface liquids, together with their contents of cell products, plasma pro...
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Chapter
Inflammation in Rhinitis
Rhinitis and asthma are common diseases which are increasing both in terms of occurrence and severity. The pathophysiology and pharmacology of these diseases suggest that inflammatory processes have a primary ...
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Article
Plasma exudation in the skin measured by external detection of conversion electrons
A novel technique for measurement of plasma exudation in the skin is described. Transferrin labelled in vivo with indium-113m is used as a plasma tracer. The conversion electrons from113mIn are detected with a po...