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within L. A. Malchenko Remove this filter Animal Anatomy / Morphology / Histology Remove this filter

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  1. No Access

    Article

    Analysis of the Ovarian Marker Genes Expression Revealed the Antagonistic Effects of Serotonin and Androstenedione on the Functional State of Mouse Granulosa Cells in Primary Culture

    Primary culture of granulosa cells is a prerequisite for a complete study of the normal functioning of the ovary and its pathologies. In this work, we selected the optimal protocol for obtaining a primary cult...

    N. M. Alyoshina, V. R. Rousanova… in Russian Journal of Developmental Biology (2023)

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    Article

    Oocyte-Mediated Effect of Serotonin on the Functional Status of Granulosa Cells

    In the mammalian ovary, serotonin has all the components necessary for its signaling function and affects the functional activity of granulosa cells. At the same time, the accumulation of serotonin with the he...

    D. A. Nikishin, Y. V. Khramova, N. M. Alyoshina… in Russian Journal of Developmental Biology (2021)

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    Article

    The Administration of Semax and HLDF-6 Peptides to Rats Regulates Protein Synthesis Rhythm in Hepatocytes and Corrects Senescent Disturbances

    To clarify the organizing effect of Semax and HLDF-6 peptides on the kinetics of protein synthesis in hepatocytes, in addition to an in vitro study (Brodsky et al., 2019), the effects of these peptides in vivo...

    V. Y. Brodsky, Y. A. Zolotarev, L. A. Malchenko… in Russian Journal of Developmental Biology (2020)

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    Article

    Neuroprotective Peptides Regulate Protein-Synthesis Kinetics in Hepatocytes of Different Age Rats

    In the search for stable factors regulating direct cell–cell interactions and effects on the properties of cells in aging organisms, the regulatory peptides Semax and HLDF-6 were studied. The circahoralian rhy...

    V. Y. Brodsky, Y. A. Zolotarev, L. A. Malchenko… in Russian Journal of Developmental Biology (2019)

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    Article

    Melatonin injected into rat efficiently synchronizes the rhythm of protein synthesis in primary hepatocyte cultures isolated from this rat

    Melatonin injected intraperitoneally into rat synchronizes the ultradian rhythm of protein synthesis after 100 min in primary hepatocyte cultures isolated from this rat, which are studied after 1 or 2 days. Th...

    V. Ya. Brodsky, S. I. Rapoport, T. K. Dubovaya… in Russian Journal of Developmental Biology (2010)