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Article
Revisiting the T-cell receptor alpha/delta locus and possible associations with multiple sclerosis
A role for T cells in the pathogenesis of multiple sclerosis (MS) is well supported, evidenced by myriad immunological studies, as well as the unequivocal genetic influence of the major histocompatibility comp...
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Article
Regulation of major histocompatibility complex class II gene expression, genetic variation and disease
Major histocompatibility complex (MHC) class II molecules are central to adaptive immune responses and maintenance of self-tolerance. Since the early 1970s, the MHC class II region at chromosome 6p21 has been ...