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  1. No Access

    Article

    fMRI and corpus callosum relationships in monozygotic twins discordant for handedness

    To further investigate brain structure and function in 26 handedness discordant monozygotic twin pairs (MzHd), MRI and behavioural assessments were carried out. These showed significant correlation between lan...

    J. M. Gurd, P. E. Cowell, S. Lux, R. Rezai, L. Cherkas… in Brain Structure and Function (2013)

  2. No Access

    Article

    Revisiting the T-cell receptor alpha/delta locus and possible associations with multiple sclerosis

    A role for T cells in the pathogenesis of multiple sclerosis (MS) is well supported, evidenced by myriad immunological studies, as well as the unequivocal genetic influence of the major histocompatibility comp...

    C T Watson, A E Para, M R Lincoln, S V Ramagopalan, S M Orton… in Genes & Immunity (2011)

  3. No Access

    Article

    Regulation of major histocompatibility complex class II gene expression, genetic variation and disease

    Major histocompatibility complex (MHC) class II molecules are central to adaptive immune responses and maintenance of self-tolerance. Since the early 1970s, the MHC class II region at chromosome 6p21 has been ...

    L Handunnetthi, S V Ramagopalan, G C Ebers, J C Knight in Genes & Immunity (2010)

  4. Article

    MS and autoimmune disorders

    G. C. Ebers in neurogenetics (2009)

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  5. No Access

    Article

    EVI5 is a risk gene for multiple sclerosis

    HLA-DRB1 is the major locus associated with risk for multiple sclerosis (MS). A recent genome-wide study showed three additional single-nucleotide polymorphisms (SNPs), within the IL2RA and IL7RA genes respect...

    I A Hoppenbrouwers, Y S Aulchenko, G C Ebers, S V Ramagopalan… in Genes & Immunity (2008)

  6. No Access

    Article

    The role of hereditary spastic paraplegia related genes in multiple sclerosis

    Multiple sclerosis (MS) is a common inflammatory disease of the central nervous system unsurpassed for its variability in disease outcome. It has been observed that axonal loss in MS is significant and that ir...

    G. C. DeLuca, S. V. Ramagopalan, M. Z. Cader, D. A. Dyment… in Journal of Neurology (2007)

  7. No Access

    Article

    Follow-up investigation of 12 proposed linkage regions in multiple sclerosis

    Multiple sclerosis (MS) is an autoimmune disease with overwhelming evidence for genetic determination, and for which a maternal parent-of-origin effect has been reported. As with many complex diseases, multipl...

    B M Herrera, M Z Cader, D A Dyment, J T Bell, S V Ramagopalan… in Genes & Immunity (2006)

  8. No Access

    Article

    TCR β polymorphisms and multiple sclerosis

    A total of 267 families with two or more siblings with multiple sclerosis (MS) were genotyped with 14 restriction fragment length polymorphisms at the TCR β locus. A nonparametric linkage analysis of the data ...

    D A Dyment, J L Steckley, K Morrison, C J Willer, M Z Cader, G C DeLuca… in Genes & Immunity (2004)

  9. No Access

    Article

    The natural history of multiple sclerosis

    The natural history of chronic diseases is generally poorly understood. Multiple sclerosis os one of the best-studied diseases and we outline here some of the information obtained from 25 000 patient-years of...

    G.C. Ebers in Neurological Sciences (2000)

  10. No Access

    Article

    A genetic basis for familial aggregation in multiple sclerosis

    GENETIC-environmental interactions probably underlie spontaneous human autoimmune disorders, a category of complex traits thought to include multiple sclerosis (MS)1. The geographical distribution and familial ag...

    G. C. Ebers, A. D. Sadovnick, N. J. Risch in Nature (1995)

  11. No Access

    Chapter and Conference Paper

    Studies of the Natural History of Multiple Sclerosis

    Investigators conducting clinical therapeutic trials in patients with multiple sclerosis (MS) are often surprised at the favorable outcome of their control groups [1, 2]. Numerous ongoing trials address the tr...

    B. Weinshenker, B. Bass, G. C. Ebers in Virology and Immunology in Multiple Sclero… (1988)

  12. No Access

    Article

    Irish neurological association

    M. A. Farrell, G. C. Ebers, C. Anderson, C. Keohane… in Irish Journal of Medical Science (1987)

  13. No Access

    Article

    Severe cerebellar degeneration in a patient with T-cell lymphoma

    A 53-year-old man with an aggressive T-cell lymphoma was found at autopsy to have severe cerebellar degeneration, presumably as a ‘remote’ effect of malignancy. The degree of cerebellar atrophy was unusually p...

    L. C. Ang, D. W. Zochodne, G. C. Ebers, J. C. E. Kaufmann… in Acta Neuropathologica (1986)