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Article
Magmatic to aqueous phase transition in Li-pegmatite: microtextural and geochemical study of muscovite–lepidolite from Boam mine area, Ul**, South Korea
This study investigated the Boam mine area, a prominent Li-pegmatite deposits located in South Korea, using Li-bearing micas to determine the magmatic–aqueous transition involved in rare-element pegmatite form...
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Article
Open AccessQuantitative prediction of radiographic progression in patients with axial spondyloarthritis using neural network model in a real-world setting
Predicting radiographic progression in axial spondyloarthritis (axSpA) remains limited because of the complex interaction between multiple associated factors and individual variability in real-world settings. ...
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Article
Exposure Levels and Contributing Factors of Various Arsenic Species and Their Health Effects on Korean Adults
Arsenic is a human carcinogen. Data on urinary arsenic species analyses of Koreans are limited. This study evaluated the arsenic exposure level, contributing factors, and health effects in Korean adults. Dieta...
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Article
Open AccessIntegrative analysis of lung molecular signatures reveals key drivers of idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a devastating disease with a high clinical burden. The molecular signatures of IPF were analyzed to distinguish molecular subgroups and identify key driver genes and ther...
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Article
Pregnancy rates and perinatal outcomes in women with systemic lupus erythematosus: data from the Korean national health claims database
The pregnancy rate in systemic lupus erythematosus (SLE) is not fully understood and comparisons of adverse pregnancy outcomes (APOs) with SLE versus the general population are limited. This study aimed to est...
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Article
Open AccessAuthor Correction: Network-based modeling of drug effects on disease module in systemic sclerosis
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Open AccessInfluenza infection as a trigger for systemic lupus erythematosus flares resulting in hospitalization
In patients with systemic lupus erythematosus (SLE), there are concerns that infections may increase the risk of flares. We evaluated the association between influenza infection and SLE flares resulting in hos...
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Article
Risk factors for cervical spine instability in patients with rheumatoid arthritis
Cervical spine (C-spine) instability is a unique and significant characteristic of rheumatoid arthritis (RA) because its occurrence is not rare and it can cause compressive cervical myelopathy, which may lead ...
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Article
Open AccessNetwork-based modeling of drug effects on disease module in systemic sclerosis
The network-based proximity between drug targets and disease genes can provide novel insights regarding the repercussions, interplay, and repositioning of drugs in the context of disease. Current understanding...
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Article
Machine learning–based prediction of radiographic progression in patients with axial spondyloarthritis
Machine learning is applied to characterize the risk and predict outcomes in multi-dimensional data. The prediction of radiographic progression in axial spondyloarthritis (axSpA) remains limited. Hence, we tes...
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Article
Open AccessIntegrated systems analysis of salivary gland transcriptomics reveals key molecular networks in Sjögren’s syndrome
Treatment of patients with Sjögren’s syndrome (SjS) is a clinical challenge with high unmet needs. Gene expression profiling and integrative network-based approaches to complex disease can offer an insight on ...
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Article
Association of cumulative anti-cyclic citrullinated protein antibodies with radiographic progression in patients with rheumatoid arthritis
Antibody against cyclic citrullinated protein (ACPA) is counted as one of the most important biomarkers in diagnosis, classification, and prognosis of rheumatoid arthritis (RA). We examined the evolution of AC...
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Article
Open AccessRespiratory viral infections and the risk of rheumatoid arthritis
We aimed to investigate the effects of ambient respiratory viral infections in the general population on rheumatoid arthritis (RA) development.
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Article
Open AccessLong-term efficacy, safety and immunogenicity in patients with rheumatoid arthritis continuing on an etanercept biosimilar (LBEC0101) or switching from reference etanercept to LBEC0101: an open-label extension of a phase III multicentre, randomised, double-blind, parallel-group study
To evaluate the long-term efficacy, safety and immunogenicity of continuing LBEC0101; the etanercept (ETN) biosimilar; or switching from the ETN reference product (RP) to LBEC0101 in patients with rheumatoid a...
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Article
Effect of dietary patterns on the blood/urine concentration of the selected toxic metals (Cd, Hg, Pb) in Korean children
This study was aimed to examine the association the blood/urinary concentration of toxic metal (Hg, Pb, and Cd) with children’s dietary patterns. This cross-sectional study included 1026 school children aged 8...
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Article
Low-Level Environmental Cadmium Exposure Induces Kidney Tubule Damage in the General Population of Korean Adults
Cadmium (Cd) is the most potent nephrotoxic heavy metal and may affect bone; it also has a long biological half-life in the human body. This study was designed to assess the effect of environmental low-level C...
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Internal Flow Characteristics and Low-Frequency Instability in Hybrid Rocket Combustion
The present study addressed the role of internal flow dynamics in determining regression rate and low-frequency instability in hybrid rocket. The first part was mainly devoted to examine the internal flow char...
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Article
Open AccessVisceral fat obesity is highly associated with primary gout in a metabolically obese but normal weighted population: a case control study
Gout is a chronic inflammatory disease the development of which is associated with obesity-induced metabolic abnormalities. However, a substantial number of non-obese patients (body mass index [BMI] <25 kg/m2) al...
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Article
Determination of toxic heavy metal levels in commonly consumed species of shrimp and shellfish using ICP-MS/OES
Toxic metal concentrations, including lead (Pb), cadmium (Cd), aluminum (Al), mercury (Hg), and arsenic (As) in edible tissues of different species of shrimp and shellfish consumed in South Korea were analyzed...
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Article
Reference levels of blood mercury and association with metabolic syndrome in Korean adults
Mercury (Hg) is a nonessential and toxic metal that is widely distributed in the environment. This study was performed to estimate the representative blood Hg level, to determine the contributing factors to Hg...
