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Article
Open AccessThe acute phase reactant orosomucoid-2 directly promotes rheumatoid inflammation
Acute phase proteins involved in chronic inflammatory diseases have not been systematically analyzed. Here, global proteome profiling of serum and urine revealed that orosomucoid-2 (ORM2), an acute phase react...
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Article
Open AccessEffectiveness and safety of adalimumab in patients with intestinal Behçet’s disease: a real-world prospective observational study in South Korea
Intestinal Behçet’s disease (BD) is characterized by typical gastrointestinal ulcers in patients with BD followed by complications such as bleeding, perforation and fistula. Biologic agents are currently under...
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Article
Open AccessQuantitative prediction of radiographic progression in patients with axial spondyloarthritis using neural network model in a real-world setting
Predicting radiographic progression in axial spondyloarthritis (axSpA) remains limited because of the complex interaction between multiple associated factors and individual variability in real-world settings. ...
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Article
Open AccessEffect of resistance exercise on serum leptin levels in a prospective longitudinal study of women patients with rheumatoid arthritis
Exercise has an anti-inflammatory effect and reduces fat mass. Leptin has been known to be proinflammatory adipokines mainly produced by adipocytes. However, few studies have investigated the association betwe...
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Article
Open AccessAccelerated diastolic dysfunction in premenopausal women with rheumatoid arthritis
Disturbances of diastolic function precede systolic heart failure and, although clinically silent, represent the earliest sign of cardiac involvement. Diastolic dysfunction (DD) is associated with age, gender ...
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Article
Pregnancy rates and perinatal outcomes in women with systemic lupus erythematosus: data from the Korean national health claims database
The pregnancy rate in systemic lupus erythematosus (SLE) is not fully understood and comparisons of adverse pregnancy outcomes (APOs) with SLE versus the general population are limited. This study aimed to est...
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Article
Open AccessInfluenza infection as a trigger for systemic lupus erythematosus flares resulting in hospitalization
In patients with systemic lupus erythematosus (SLE), there are concerns that infections may increase the risk of flares. We evaluated the association between influenza infection and SLE flares resulting in hos...
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Article
Machine learning–based prediction of radiographic progression in patients with axial spondyloarthritis
Machine learning is applied to characterize the risk and predict outcomes in multi-dimensional data. The prediction of radiographic progression in axial spondyloarthritis (axSpA) remains limited. Hence, we tes...
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Article
Association of cumulative anti-cyclic citrullinated protein antibodies with radiographic progression in patients with rheumatoid arthritis
Antibody against cyclic citrullinated protein (ACPA) is counted as one of the most important biomarkers in diagnosis, classification, and prognosis of rheumatoid arthritis (RA). We examined the evolution of AC...
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Article
Open AccessRespiratory viral infections and the risk of rheumatoid arthritis
We aimed to investigate the effects of ambient respiratory viral infections in the general population on rheumatoid arthritis (RA) development.
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Article
Open AccessUrinary interleukin-6 as a predictor of radiographic progression in rheumatoid arthritis: A 3-year evaluation
Previously, we demonstrated that the urine proteome signature of patients with rheumatoid arthritis (RA) reflects inflammation-related cellular processes. Here, we measured interleukin (IL)-6, IL-8, and chemok...
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Article
Open AccessIdentification of novel urinary biomarkers for assessing disease activity and prognosis of rheumatoid arthritis
To optimize treatment for rheumatoid arthritis (RA), it is ideal to monitor the disease activity on a daily basis because RA activity fluctuates over time. Urine can be collected routinely at home by patients....
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Article
Ultrasonography is useful to detect subclinical synovitis in SLE patients without musculoskeletal involvement before symptoms appear
The purpose of this study is to investigate the frequency of the subclinical synovitis in hand or wrist joints of the SLE patients using ultrasonography (US) and to correlate them with clinical parameters. For...
