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Article
Open AccessDesigning a novel and combinatorial multi-antigenic epitope-based vaccine “MarVax” against Marburg virus—a reverse vaccinology and immunoinformatics approach
Marburg virus (MARV) is a member of the Filoviridae family and causes Marburg virus disease (MVD) among humans and primates. With fatality rates going up to 88%, there is currently no commercialized cure or va...
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Article
Open AccessAssociated production of Higgs and single top at the LHC in presence of the SMEFT operators
We analyse the single top production in association with the Higgs at the Large Hadron Collider (LHC) using Standard Model (SM) effective operators upto dimension six. We show that the presence of effective op...
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Article
Open AccessRegularizing the JNW and JMN naked singularities
We extend the method of Simpson and Visser (SV) of regularizing a black hole spacetime, to cases where the initial metric represents a globally naked singularity. We choose two particular geometries, the Janis...
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Article
Exploring the pharmacological aspects of natural phytochemicals against SARS-CoV-2 Nsp14 through an in silico approach
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), possesses an important bifunctional nonstructural protein (nsp14) with a C-terminal N7-methyltransferase (N7-MTase) domain and an N-terminal do...
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Article
Open AccessDisformal transformations and the motion of a particle in semi-classical gravity
The approach to incorporate quantum effects in gravity by replacing free particle geodesics with Bohmian non-geodesic trajectories has an equivalent description in terms of a conformally related geometry, wher...
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Article
Open AccessCollapse in f(R) gravity and the method of R matching
Collapsing solutions in f(R) gravity are restricted due to junction conditions that demand continuity of the Ricci scalar and its normal derivative across the time-like collapsing hypersurface. These are obtained...
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Article
Open AccessMolecular assembly of rhodopsin with G protein-coupled receptor kinases
G protein-coupled receptor kinases (GRKs) play pivotal roles in desensitizing GPCR signaling but little is known about how GRKs recognize and phosphorylate GPCRs due to the technical difficulties in detecting ...
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Article
Structure and mechanism for recognition of peptide hormones by Class B G-protein-coupled receptors
Class B G-protein-coupled receptors (GPCRs) are receptors for peptide hormones that include glucagon, parathyroid hormone, and calcitonin. These receptors are involved in a wide spectrum of physiological activ...
