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    Article

    Understanding the Molecular Regulation of Serotonin Receptor 5-HTR1B-β-Arrestin1 Complex in Stress and Anxiety Disorders

    The serotonin receptor subtype 5-HTR1B is widely distributed in the brain with an important role in various behavioral implications including neurological conditions and psychiatric disorders. The neuromodulatory...

    Oindrilla Dutta Gupta, Izhar Karbat, Kuntal Pal in Journal of Molecular Neuroscience (2023)

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    Article

    miRNA regulation of G protein-coupled receptor mediated angiogenic pathways in cancer

    Angiogenesis is an important biological process associated with plethora of physiological and patho-physiological conditions. Recent data suggests that fine balance between anti-angiogenic microRNA (miRNA) and...

    Samanwita Mandal, Deblina Chakrabarty, Arijit Bhattacharya, Joydeep Paul in The Nucleus (2021)

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    Article

    A complex structure of arrestin-2 bound to a G protein-coupled receptor

    Arrestins comprise a family of signal regulators of G-protein-coupled receptors (GPCRs), which include arrestins 1 to 4. While arrestins 1 and 4 are visual arrestins dedicated to rhodopsin, arrestins 2 and 3 (...

    Wanchao Yin, Zhihai Li, Mingliang **, Yu-Ling Yin, Parker W. de Waal in Cell Research (2019)

  4. Article

    Open Access

    Molecular assembly of rhodopsin with G protein-coupled receptor kinases

    G protein-coupled receptor kinases (GRKs) play pivotal roles in desensitizing GPCR signaling but little is known about how GRKs recognize and phosphorylate GPCRs due to the technical difficulties in detecting ...

    Yuanzheng He, **ang Gao, Devrishi Goswami, Li Hou, Kuntal Pal, Yanting Yin in Cell Research (2017)