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Article
Open AccessEffects of an 18-month community-based, multifaceted, exercise program on patient-reported outcomes in older adults at risk of fracture: secondary analysis of a randomised controlled trial
This study identified that an 18-month community-based, multifaceted, exercise program consisting of resistance, weight-bearing impact, and balance/mobility training combined with osteoporosis education and be...
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Article
Open AccessAn experience- and preference-based EQ-5D-3L value set derived using 18 months of longitudinal data in patients who sustained a fracture: results from the ICUROS
EQ-5D-3L preference-based value sets are predominately based on hypothetical health states and derived in cross-sectional settings. Therefore, we derived an experience-based value set from a prospective observ...
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Article
Recovery of quality of life is associated with lower mortality 5-year post-fracture: the Australian arm of the International Costs and Utilities Related to Osteoporotic Fractures Study (AusICUROS)
Little is known about factors that lead to excess mortality post-fracture. This study demonstrated that 5-year mortality is lower in older adults who recovered to their pre-fracture health-related quality of l...
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Article
Effects of a multi-modal resistance exercise program and calcium-vitamin D3 fortified milk on blood pressure and blood lipids in middle-aged and older men: secondary analysis of an 18-month factorial design randomised controlled trial
Physical activity and dietary interventions are recommended as front-line therapy for prevention and management of cardiovascular disease. This study investigated the independent and combined effects of low-fa...
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Article
Do replicable profiles of multimorbidity exist? Systematic review and synthesis
This systematic review aimed to synthesise multimorbidity profiling literature to identify replicable and clinically meaningful grou**s of multimorbidity. We searched six electronic databases (Medline, EMBAS...
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Article
Open AccessStrategies and challenges associated with recruiting retirement village communities and residents into a group exercise intervention
Randomized controlled trials (RCTs) provide the highest level of scientific evidence, but successful participant recruitment is critical to ensure the external and internal validity of results. This study desc...
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Article
Open AccessArthritis diagnosis and symptoms are positively associated with specific physical job exposures in lower- and middle-income countries: cross-sectional results from the World Health Organization’s Study on global AGEing and adult health (SAGE)
In higher income countries, work-related squatting and heavy lifting have been associated with increased arthritis risk. Here, we address the paucity of data regarding associations between arthritis and work-r...
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Article
Quality of life after hip, vertebral, and distal forearm fragility fractures measured using the EQ-5D-3L, EQ-VAS, and time-trade-off: results from the ICUROS
The International Costs and Utilities Related to Osteoporotic fractures Study is a multinational observational study set up to describe the costs and quality of life (QoL) consequences of fragility fracture. T...
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Article
Associations between illness duration and health-related quality of life in specified mental and physical chronic health conditions: results from a population-based survey
We compared health-related quality of life (HRQOL) in incident (≤1 year since diagnosis), mid-term (>1–5 years since diagnosis), and long-term (>5 years since diagnosis) cases of mental and physical chronic il...
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Article
The effect of vitamin D status on pain, lower limb strength and knee function during balance recovery in people with knee osteoarthritis: an exploratory study
The association between vitamin D and muscle function associated with balance recovery and falls in people with knee osteoarthritis is unclear. Those with vitamin D insufficiency demonstrated poorer knee funct...
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Article
Adiposity assessed by anthropometric measures has a similar or greater predictive ability than dual-energy X-ray absorptiometry measures for abdominal aortic calcification in community-dwelling older adults
To determine whether adiposity assessed by dual-energy X-ray absorptiometry (DXA) compared to simple anthropometric assessments, are more predictive of abdominal aortic calcification (AAC), a risk factor for a...
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Article
Open AccessFew geographic and socioeconomic variations exist in primary total shoulder arthroplasty: a multi-level study of Australian registry data
Associations between socioeconomic position (SEP) and the uptake of primary total shoulder arthroplasty (TSA) is not well understood in the Australian population, thus potentially limiting equitable allocation...
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Article
New findings on vitamin D3 supplementation and falls — when more is perhaps not better
Results from a recent randomized controlled trial on vitamin D3 supplementation suggest that even modestly high doses of vitamin D3, when given once monthly, might be associated with an increased rate of falls in...
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Article
Humeral Fractures in South-Eastern Australia: Epidemiology and Risk Factors
In this study, we report the epidemiology and risk factors for humeral fractures (proximal humerus and shaft) among men and women residing in south-eastern Australia. Incident fractures during 2006 and 2007 w...
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Article
Fall and Fracture Risk in Sarcopenia and Dynapenia With and Without Obesity: the Role of Lifestyle Interventions
Due to their differing etiologies and consequences, it has been proposed that the term “sarcopenia” should revert to its original definition of age-related muscle mass declines, with a separate term, “dynapeni...
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Article
Open AccessAssociations between socioeconomic status and primary total knee joint replacements performed for osteoarthritis across Australia 2003–10: data from the Australian Orthopaedic Association National Joint Replacement Registry
Relatively little is known about the social distribution of total knee joint replacement (TKR) uptake in Australia. We examine associations between socioeconomic status (SES) and TKR performed for diagnosed os...
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Article
Vitamin D Deficiency and its Role in Muscle-Bone Interactions in the Elderly
In this commentary, we focus on common ‘downstream’ links of vitamin D between muscle and bone health. Both direct and indirect effects of 1,25 dihydroxyvitamin D (1,25(OH)D) link the mutual age-related declin...
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Article
Is High-Dose Vitamin D Harmful? Authors’ Reply
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Article
Is High Dose Vitamin D Harmful?
With the potential to minimize the risk of many chronic diseases and the apparent biochemical safety of ingesting doses of oral vitamin D several-fold higher than the current recommended intakes, recent resear...
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Article
Open AccessOsteo-cise: Strong Bones for Life: Protocol for a community-based randomised controlled trial of a multi-modal exercise and osteoporosis education program for older adults at risk of falls and fractures
Osteoporosis affects over 220 million people worldwide, and currently there is no ‘cure’ for the disease. Thus, there is a need to develop evidence-based, safe and acceptable prevention strategies at the popul...
