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  1. Article

    Open Access

    A holistic lifestyle mobile health intervention for the prevention of type 2 diabetes and common mental disorders in Asian women with a history of gestational diabetes: a randomised control trial with 3-year follow-up protocol

    Women with a history of gestational diabetes mellitus (GDM) are 12-fold more likely to develop type 2 diabetes (T2D) 4–6 years after delivery than women without GDM. Similarly, GDM is associated with the devel...

    Alicia Salamanca-Sanabria, Seaw Jia Liew, Jacqueline Mair, Maria De Iorio in Trials (2024)

  2. Article

    Open Access

    Automatic segmentation of tumour and organs at risk in 3D MRI for cervical cancer radiation therapy with anatomical variations

    Cervical cancer is a common cancer in women globally, with treatment usually involving radiation therapy (RT). Accurate segmentation for the tumour site and organ-at-risks (OARs) could assist in the reduction ...

    Sze-Nung Leung, Shekhar S. Chandra in Physical and Engineering Sciences in Medic… (2024)

  3. Article

    Open Access

    Feasibility and preliminary efficacy of iConquerFear: a self-guided digital intervention for fear of cancer recurrence

    Approximately 50% of cancer survivors experience moderate-severe fear of cancer recurrence (FCR). Self-guided digital interventions have potential to address the high level of FCR-related unmet needs at scale,...

    Allan ‘Ben’ Smith, Adeola Bamgboje‐Ayodele in Journal of Cancer Survivorship (2024)

  4. No Access

    Chapter

    Rapid Detection of Foetal Mendelian Disorders: Thalassaemia and Sickle Cell Syndrome

    Haemoglobinopathies collectively represent the most common group of inherited single-gene disorders, affecting up to 332,000 births annually. Individuals who carry the genetic mutation may be asymptomatic carr...

    Karen Lim, Mahesh Choolani in Prenatal Diagnostic Testing for Genetic Disorders (2023)

  5. Article

    Open Access

    Increased retinal venular calibre in acute infections

    Population-based studies have demonstrated that increased retinal venular calibre is a risk factor for cardiac disease, cardiac events and stroke. Venular dilatation also occurs with diabetes, obesity, dyslipi...

    Cara Fitt, Thao Vi Luong, Damian Cresp, Anastasia Hutchinson in Scientific Reports (2021)

  6. No Access

    Article

    Do replicable profiles of multimorbidity exist? Systematic review and synthesis

    This systematic review aimed to synthesise multimorbidity profiling literature to identify replicable and clinically meaningful grou**s of multimorbidity. We searched six electronic databases (Medline, EMBAS...

    Ljoudmila Busija, Karen Lim, Cassandra Szoeke in European Journal of Epidemiology (2019)

  7. Article

    Open Access

    Smart Phone APP to Restore Optimal Weight (SPAROW): protocol for a randomised controlled trial for women with recent gestational diabetes

    Gestational diabetes (GDM) is a known risk factor for type 2 diabetes mellitus (T2DM), and women with a history of GDM have a 7-fold increased risk of develo** the disease. Achieving a healthy weight post-de...

    Karen Lim, Claudia Chi, Shiao-Yng Chan, Su Lin Lim, Siew Min Ang in BMC Public Health (2019)

  8. No Access

    Article

    Utilising pseudo-CT data for dose calculation and plan optimization in adaptive radiotherapy

    To quantify the dose calculation error and resulting optimization uncertainty caused by performing inverse treatment planning on inaccurate electron density data (pseudo-CT) as needed for adaptive radiotherapy...

    Brendan Whelan, Shivani Kumar, Jason Dowling in Australasian Physical & Engineering Scienc… (2015)

  9. No Access

    Chapter

    Bridging the Gaps between European and Chinese Civil Societies

    The above quote is indicative of an increasing consensus among concerned China scholars that there is a dire need for innovative solutions to bridge the communication and collaboration gap between Europe and C...

    Mark Pixley, Karen Lim in Civil Society Contributions to Policy Innovation in the PR China (2015)

  10. No Access

    Chapter and Conference Paper

    Chaotic Analysis of Epileptic EEG Signals

    Electroencephalogram (EEG) is the recording of the electrical activity of the brain. One of the major fields of application of this relatively cheap and non-invasive diagnostic technique is epilepsy, which aff...

    N. Kannathal, Johnny Chee, Kenneth Er in The 15th International Conference on Biome… (2014)

  11. No Access

    Chapter and Conference Paper

    A Survey of Cervix Segmentation Methods in Magnetic Resonance Images

    Radiotherapy is an effective therapy in the treatment of cervix cancer. However tumor and normal tissue motion and shape deformation of the cervix, the bladder and the rectum over the course of the treatment c...

    Soumya Ghose, Lois Holloway, Karen Lim in Abdominal Imaging. Computation and Clinica… (2013)

  12. No Access

    Chapter

    Image-Guidance in External Beam Planning for Locally Advanced Cervical Cancer

    The use of highly conformal external beam radiotherapy may decrease toxicity and enhance tumor control. However, the marked tumor regression seen in cervix cancer during radiotherapy, combined with the complex...

    Karen Lim, Michael Milosevic, Kristy Brock, Anthony Fyles in Gynecologic Radiation Therapy (2011)

  13. No Access

    Article

    Selective antagonism of dopamine D1 and D2 receptors does not block the development of behavioral sensitization to cocaine

    The objective of this study was to determine whether the development of behavioral sensitization to cocaine could be prevented by either D1 or D2 selective dopamine receptor antagonists. Male Wistar rats were tre...

    Bruce A. Mattingly, Tamara C. Hart, Karen Lim, Carmen Perkins in Psychopharmacology (1994)