-
Article
Open AccessA holistic lifestyle mobile health intervention for the prevention of type 2 diabetes and common mental disorders in Asian women with a history of gestational diabetes: a randomised control trial with 3-year follow-up protocol
Women with a history of gestational diabetes mellitus (GDM) are 12-fold more likely to develop type 2 diabetes (T2D) 4–6 years after delivery than women without GDM. Similarly, GDM is associated with the devel...
-
Article
Open AccessAutomatic segmentation of tumour and organs at risk in 3D MRI for cervical cancer radiation therapy with anatomical variations
Cervical cancer is a common cancer in women globally, with treatment usually involving radiation therapy (RT). Accurate segmentation for the tumour site and organ-at-risks (OARs) could assist in the reduction ...
-
Article
Open AccessFeasibility and preliminary efficacy of iConquerFear: a self-guided digital intervention for fear of cancer recurrence
Approximately 50% of cancer survivors experience moderate-severe fear of cancer recurrence (FCR). Self-guided digital interventions have potential to address the high level of FCR-related unmet needs at scale,...
-
Chapter
Rapid Detection of Foetal Mendelian Disorders: Thalassaemia and Sickle Cell Syndrome
Haemoglobinopathies collectively represent the most common group of inherited single-gene disorders, affecting up to 332,000 births annually. Individuals who carry the genetic mutation may be asymptomatic carr...
-
Article
Open AccessIncreased retinal venular calibre in acute infections
Population-based studies have demonstrated that increased retinal venular calibre is a risk factor for cardiac disease, cardiac events and stroke. Venular dilatation also occurs with diabetes, obesity, dyslipi...
-
Article
Do replicable profiles of multimorbidity exist? Systematic review and synthesis
This systematic review aimed to synthesise multimorbidity profiling literature to identify replicable and clinically meaningful grou**s of multimorbidity. We searched six electronic databases (Medline, EMBAS...
-
Article
Open AccessSmart Phone APP to Restore Optimal Weight (SPAROW): protocol for a randomised controlled trial for women with recent gestational diabetes
Gestational diabetes (GDM) is a known risk factor for type 2 diabetes mellitus (T2DM), and women with a history of GDM have a 7-fold increased risk of develo** the disease. Achieving a healthy weight post-de...
-
Article
Utilising pseudo-CT data for dose calculation and plan optimization in adaptive radiotherapy
To quantify the dose calculation error and resulting optimization uncertainty caused by performing inverse treatment planning on inaccurate electron density data (pseudo-CT) as needed for adaptive radiotherapy...
-
Chapter
Bridging the Gaps between European and Chinese Civil Societies
The above quote is indicative of an increasing consensus among concerned China scholars that there is a dire need for innovative solutions to bridge the communication and collaboration gap between Europe and C...
-
Chapter and Conference Paper
Chaotic Analysis of Epileptic EEG Signals
Electroencephalogram (EEG) is the recording of the electrical activity of the brain. One of the major fields of application of this relatively cheap and non-invasive diagnostic technique is epilepsy, which aff...
-
Chapter and Conference Paper
A Survey of Cervix Segmentation Methods in Magnetic Resonance Images
Radiotherapy is an effective therapy in the treatment of cervix cancer. However tumor and normal tissue motion and shape deformation of the cervix, the bladder and the rectum over the course of the treatment c...
-
Chapter
Image-Guidance in External Beam Planning for Locally Advanced Cervical Cancer
The use of highly conformal external beam radiotherapy may decrease toxicity and enhance tumor control. However, the marked tumor regression seen in cervix cancer during radiotherapy, combined with the complex...
-
Article
Selective antagonism of dopamine D1 and D2 receptors does not block the development of behavioral sensitization to cocaine
The objective of this study was to determine whether the development of behavioral sensitization to cocaine could be prevented by either D1 or D2 selective dopamine receptor antagonists. Male Wistar rats were tre...