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  1. Article

    Open Access

    Risk of metachronous colorectal cancer after surgical resection of index rectal cancer in Lynch syndrome: a multicenter retrospective study in Japan

    This study evaluated the risk of metachronous colorectal cancer (CRC) after resection of index (first) rectal cancer in patients with Lynch syndrome (LS).

    Kenichi Chikatani, Hideyuki Ishida, Yoshiko Mori, Takeshi Nakajima… in Surgery Today (2024)

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    Article

    Clinical features and distribution of the APC variant in duodenal and ampullary polyps in patients with familial adenomatous polyposis: a multicenter retrospective cohort study in Japan

    Management of duodenal or ampullary adenomas in patients with familial adenomatous polyposis (FAP) is a major challenge for clinicians. Insufficient data are available to evaluate the clinical manifestations a...

    Yasuyuki Miyakura, Tatsuro Yamaguchi… in International Journal of Clinical Oncology (2024)

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    Usefulness of genoty** APC gene for individualizing management of patients with familial adenomatous polyposis

    Colorectal polyp burden is crucial for the management of patients with familial adenomatous polyposis (FAP). However, accurate evaluation of polyp burden is difficult to standardize. This study aimed to examin...

    Yoshiko Mori, Hideyuki Ishida, Noriyasu Chika… in International Journal of Clinical Oncology (2023)

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    Article

    Risk of metachronous colorectal cancer after colectomy for first colon cancer in Lynch syndrome: multicenter retrospective study in Japan

    We evaluated the risk of metachronous colorectal cancer (mCRC) and explored the optimal extent of colectomy in patients with Lynch syndrome (LS) and first colon cancer (fCC) in Japan, where the extent of colec...

    Kenichi Chikatani, Hideyuki Ishida… in International Journal of Clinical Oncology (2023)

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    Article

    Recent trends in the morbidity and mortality in patients with familial adenomatous polyposis: a retrospective single institutional study in Japan

    This study aimed to assess current trends in morbidity and mortality among patients with familial adenomatous polyposis (FAP). These data can be used for optimal surveillance and management of such patients.

    Yoshiko Mori, Kunihiko Amano… in International Journal of Clinical Oncology (2022)

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    Article

    Clinically applicable cases of anti-programmed cell death protein 1 immunotherapy for colorectal cancer patients

    We investigated the prevalence and characteristics of defective mismatch repair (dMMR) in colorectal cancer (CRC) patients who would potentially benefit from anti-programmed cell death protein 1 (PD-1) immunot...

    Kenichi Chikatani, Noriyasu Chika, Okihide Suzuki, Takehiko Sakimoto… in Surgery Today (2020)