-
Article
Open AccessAutistic traits in neurotypical adults are related to impaired perceptual–motor coordination
Individuals with autism spectrum disorder (ASD) are more prone to injury due to falls or collisions with objects. This may be caused by impaired perceptual–motor coordination, including inaccurate body-related...
-
Article
Open AccessThe fate of non-supersymmetric Gross-Neveu-Yukawa fixed point in two dimensions
We investigate the fate of the non-supersymmetric Gross-Neveu-Yukawa fixed point found by Fei et al. in 4 − ϵ dimensions with a two-component Majorana fermion continued to two dimensions. Assuming that it is a fe...
-
Article
Open AccessFirst case of a renal cyst infection caused by Desulfovibrio: a case report and literature review
Genus Desulfovibrio species is a sulphate-reducing anaerobic gram-negative rod that resides in the human oral cavity and intestinal tract. It was reported as the causative pathogen of bacteraemia and abdominal in...
-
Article
Open AccessBacteremia caused by Enterobacter asburiae misidentified biochemically as Cronobacter sakazakii and accurately identified by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry: a case report
Biochemical analyses of causative bacteria do not always result in clear identification, and new technologies aimed at improving diagnostic accuracy continue to be developed. Matrix-assisted laser desorption/i...
-
Article
Open AccessReduced B7-H3 expression by PAX3-FOXO1 knockdown inhibits cellular motility and promotes myogenic differentiation in alveolar rhabdomyosarcoma
B7-H3 (also known as CD276) is associated with aggressive characteristics in various cancers. Meanwhile, in alveolar rhabdomyosarcoma (ARMS), PAX3-FOXO1 fusion protein is associated with increased aggressivene...
-
Article
Open AccessNationwide surveillance of antimicrobial susceptibility of 509 rapidly growing mycobacteria strains isolated from clinical specimens in Japan
This study aimed to identify effective treatments against rapidly growing mycobacteria (RGM) infections by investigating the minimum inhibitory concentrations (MIC) of 24 antimicrobial agents and their molecul...
-
Article
Open AccessGeographical distribution and regional differences in 532 clinical isolates of rapidly growing mycobacterial species in Japan
Infectious diseases caused by nontuberculous mycobacteria (NTM) are increasingly becoming a major global problem. Additionally, Mycobacteroides abscessus subsp. abscessus (MAB) infections are refractory to macrol...
-
Article
Open AccessPulmonary infection due to fluoroquinolone-resistant Mycolicibacterium fortuitum: a case report
Mycolicibacterium fortuitum is a species of the rapidly growing mycobacteria that can cause pulmonary infection. It is susceptible to multiple antibiotics both in vitro and in clinical practice, so that any combi...
-
Article
Open AccessOncogenic role of HMGA2 in fusion-negative rhabdomyosarcoma cells
Rhabdomyosarcoma (RMS) is the most common pediatric soft tissue sarcoma. There are two subtypes, fusion gene-positive RMS (FP-RMS) and fusion gene-negative RMS (FN-RMS), depending on the presence of a fusion g...
-
Article
Open AccessPurpura fulminans with Lemierre’s syndrome caused by Gemella bergeri and Eikenella corrodens: a case report
Gemella bergeri is one of the nine species of the genus Gemella and is relatively difficult to identify. We herein describe the first case of septic shock due to a Gemella bergeri coinfection with Eikenella corro...
-
Article
Open AccessFatal Fournier’s gangrene caused by Clostridium ramosum in a patient with central diabetes insipidus and insulin-dependent diabetes mellitus: a case report
Clostridium ramosum is a generally non-pathogenic enteric anaerobe, and Fournier’s gangrene is a rare necrotizing soft tissue infection with male predisposition affecting the perineum and the genital area. We rep...
-
Article
Influence of the C5a–C5a receptor system on breast cancer progression and patient prognosis
Emerging evidence has shown activation of the complement system in cancer tissues and anaphylatoxin C5a release from C5 by cancer cells, suggesting C5a as a component in the cancer microenvironment. We reveale...
-
Article
Open AccessIGF1R as a Key Target in High Risk, Metastatic Medulloblastoma
Risk or presence of metastasis in medulloblastoma causes substantial treatment-related morbidity and overall mortality. Through the comparison of cytokines and growth factors in the cerebrospinal fluid (CSF) o...
-
Article
Comparison of integrated whole-body PET/MR and PET/CT: Is PET/MR alternative to PET/CT in routine clinical oncology?
To compare the diagnostic accuracy of whole-body PET/CT and integrated PET/MR in relation to the total scan time durations.
-
Article
Candidemia Diagnosed from Peripheral Blood Smear: Case Report and Review of Literature 1954–2013
Yeast with pseudohyphae or those that have been phagocytized by white blood cells are coincidentally found in peripheral blood smears. The clinical diagnostic value and outcome of candidaemia diagnosed from p...
-
Article
Open AccessPolytetrafluoroethylene fume–induced pulmonary edema: a case report and review of the literature
Polytetrafluoroethylene is ubiquitous in materials commonly used in cooking and industrial applications. Overheated polytetrafluoroethylene can generate toxic fumes, inducing acute pulmonary edema in some case...
-
Article
Frequent occurrence of fever in patients who have undergone endoscopic submucosal dissection for colorectal tumor, but bacteremia is not a significant cause
We examined the incidence of and factors associated with fever, as well as the frequency of bacteremia, in patients who had undergone endoscopic submucosal dissection (ESD) for colorectal tumor.
-
Article
Open AccessMethicillin-resistant Staphylococcus aureus enterocolitis sequentially complicated with septic arthritis: a case report and review of the literature
Although most reports describing patients infected with methicillin-resistant Staphylococcus aureus enterocolitis have been published in Japan, this concept remains a matter of debate and diagnostic criteria have...
-
Article
Open AccessRb1 loss modifies but does not initiate alveolar rhabdomyosarcoma
Alveolar rhabdomyosarcoma (aRMS) is a myogenic childhood sarcoma frequently associated with a translocation-mediated fusion gene, Pax3:Foxo1a.
-
Article
Hepatic resection combined with radiofrequency ablation for initially unresectable colorectal liver metastases after effective chemotherapy is a safe procedure with a low incidence of local recurrence
Chemotherapy can lead to tumor down-staging in patients with initially unresectable colorectal liver metastases (CRLM); however, more than half of such cases are still considered to be unresectable because of ...
