9 Result(s)

Article

DOCK2 is involved in the host genetics and biology of severe COVID-19

Identifying the host genetic factors underlying severe COVID-19 is an emerging challenge^1–5. Here we conducted a genome-wide association study (GWAS) involving 2,393 cases of COVID-19 in a cohort of Japanese indi...

Ho Namkoong, Ryuya Edahiro, Tomomi Takano, Hiroshi Nishihara, Yuya Shirai… in Nature (2022)

Article

The whole blood transcriptional regulation landscape in 465 COVID-19 infected samples from Japan COVID-19 Task Force

Coronavirus disease 2019 (COVID-19) is a recently-emerged infectious disease that has caused millions of deaths, where comprehensive understanding of disease mechanisms is still unestablished. In particular, s...

Qingbo S. Wang, Ryuya Edahiro, Ho Namkoong, Takanori Hasegawa… in Nature Communications (2022)

Article

Bosutinib-induced lung injury: a report of two cases and literature review

The prognosis of patients with chronic myeloid leukemia (CML) has improved dramatically since the development of tyrosine kinase inhibitors (TKIs). Three second-generation TKIs, including bosutinib, are curren...

Naoki Watanabe, Tomoiku Takaku, Yutaka Tsukune… in International Journal of Hematology (2022)

Article

Author Correction: Performance and usefulness of a novel automated immunoassay HISCL SARS-CoV-2 Antigen assay kit for the diagnosis of COVID-19

Kaori Saito, Tomohiko Ai, Akinori Kawai, Jun Matsui… in Scientific Reports (2021)

Article

Performance and usefulness of a novel automated immunoassay HISCL SARS-CoV-2 Antigen assay kit for the diagnosis of COVID-19

Here, we aimed to evaluate the clinical performance of a novel automated immunoassay HISCL SARS-CoV-2 Antigen assay kit designed to detect the nucleocapsid (N) protein of severe acute respiratory syndrome coro...

Kaori Saito, Tomohiko Ai, Akinori Kawai, Jun Matsui… in Scientific Reports (2021)

Article

High lymphocyte population-related predictive factors for a long-term response in non-small cell lung cancer patients treated with pemetrexed: a retrospective observational study

Regimens combining pemetrexed (PEM) and immune checkpoint inhibitors (ICIs) targeting programmed cell death-1 (PD-1) or programmed death-ligand 1 (PD-L1) are widely used for the treatment of advanced non-squam...

Issei Sumiyoshi, Takahiro Okabe, Shinsaku Togo… in Journal of Translational Medicine (2021)

Article

Pulmonary infection due to fluoroquinolone-resistant Mycolicibacterium fortuitum: a case report

Mycolicibacterium fortuitum is a species of the rapidly growing mycobacteria that can cause pulmonary infection. It is susceptible to multiple antibiotics both in vitro and in clinical practice, so that any combi...

Kana Kurokawa, Norihiro Harada, Hitoshi Sasano, Haruhi Takagi… in BMC Infectious Diseases (2020)

Article

Anaphylaxis to three humanized antibodies for severe asthma: a case study

Omalizumab, mepolizumab, benralizumab, and dupilumab are the currently available biologics used to treat asthma in Japan. Anaphylaxis following treatment with mepolizumab or benralizumab is considered rare.

Koichi **go, Norihiro Harada, Toshihiko Nishioki… in Allergy, Asthma & Clinical Immunology (2020)

Article

Benign giant mediastinal schwannoma presenting as cardiac tamponade in a woman: a case report

Mediastinal schwannomas are typically benign and asymptomatic, and generally present no immediate risks. We encountered a rare case of a giant benign posterior mediastinal schwannoma, complicated by life-threa...

Motoyasu Kato, Satomi Shiota, Kazuo Shiga, Haruhi Takagi… in Journal of Medical Case Reports (2011)