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    Article

    FNAIT pathogenesis determined by serial analysis of three subsequent pregnancies of a woman with severe fetal and neonatal alloimmune thrombocytopenia (FNAIT) with anti-HPA-4b and anti-HPA-5b alloantibodies in the first sibling

    Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is caused by anti-HPA alloantibody, and anti-HPA-4b is the most common cause in Japanese. Anti-HPA-5b is frequently detected in pregnant women, but it is ...

    Tomoko Kiyokawa, Kazuya Mimura, Keisuke Nagamine in International Journal of Hematology (2023)

  2. Article

    Open Access

    A male-killing gene encoded by a symbiotic virus of Drosophila

    In most eukaryotes, biparentally inherited nuclear genomes and maternally inherited cytoplasmic genomes have different evolutionary interests. Strongly female-biased sex ratios that are repeatedly observed in ...

    Daisuke Kageyama, Toshiyuki Harumoto, Keisuke Nagamine in Nature Communications (2023)

  3. Article

    Open Access

    A new antimicrobial peptide, Pentatomicin, from the stinkbug Plautia stali

    Antimicrobial peptides (AMPs) play crucial roles in the innate immunity of diverse organisms, which exhibit remarkable diversity in size, structural property and antimicrobial spectrum. Here, we describe a new...

    Yudai Nishide, Keisuke Nagamine, Daisuke Kageyama, Minoru Moriyama in Scientific Reports (2022)

  4. Article

    Open Access

    Identification of a juvenile-hormone signaling inhibitor via high-throughput screening of a chemical library

    Insecticide resistance has recently become a serious problem in the agricultural field. Development of insecticides with new mechanisms of action is essential to overcome this limitation. Juvenile hormone (JH)...

    Takumi Kayukawa, Kenjiro Furuta, Keisuke Nagamine, Tetsuro Shinoda in Scientific Reports (2020)

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    Article

    Maladaptive photoperiodic response in an invasive alien insect, Milionia basalis pryeri (Lepidoptera: Geometridae), in southern Kyushu, Japan

    The geometrid moth, Milionia basalis pryeri Druce, is an important pest of Podocarpaceae trees that has recently become established in the southern part of the main island of Kyushu, Japan. The species exhibits a...

    Yoshinori Shintani, Yoshikazu Kato, Takeo Saito, Yuji Oda in Applied Entomology and Zoology (2018)

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    Article

    Immature platelet fraction (IPF) as a predictive value for thrombopoietic recovery after allogeneic stem cell transplantation

    We consecutively examined the utility of measurements of percentage of immature platelet fraction (IPF%) and absolute IPF number (A-IPF) in predicting thrombopoietic recovery in 15 adult patients who underwent...

    Mikiko Sakuragi, Satoru Hayashi, Miho Maruyama in International Journal of Hematology (2018)

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    Article

    A method for rearing the yellow-spotted longicorn beetle, Psacothea hilaris (Coleoptera: Cerambycidae), to stabilize the last larval instar

    The larvae of Psacothea hilaris (Pascoe) grown continuously under a long day in the laboratory pupate after the 4th, 5th, or 6th instar. This developmental polymorphism has complicated studies on the control of m...

    Keisuke Nagamine, Yukio Ishikawa, Sugihiko Hoshizaki in Applied Entomology and Zoology (2017)

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    Article

    Clinical significance of IPF% or RP% measurement in distinguishing primary immune thrombocytopenia from aplastic thrombocytopenic disorders

    The diagnosis of primary immune thrombocytopenia (ITP) is based on differential diagnosis. Although the measurement of percentages of reticulated platelets (RP%) by flow cytometry is useful as a supportive dia...

    Mikiko Sakuragi, Satoru Hayashi, Miho Maruyama in International Journal of Hematology (2015)

  9. No Access

    Article

    A case of neonatal alloimmune thrombocytopenia in the presence of both anti-HPA-4b and anti-HPA-5b antibody: clinical and serological analysis of the subsequent pregnancy

    Neonatal alloimmune thrombocytopenia (NAIT) is induced by maternal alloantibodies raised against fetal platelet antigens inherited from the paternal parent. In contrast to Caucasians, in Asians, predominantly ...

    Tomoko Kiyokawa, Yangsook Koh, Kazuya Mimura in International Journal of Hematology (2014)

  10. Article

    Open Access

    Cloning, phylogeny, and expression analysis of the Broad-Complex gene in the longicorn beetle Psacothea hilaris

    Seven isoforms of Broad-Complex (PhBR-C), in which the sequence of the zinc finger domain differed (referred to as Z1, Z2, Z3, Z2/Z3, Z4, Z5/Z6, and Z6, respectively), were cloned from the yellow-spotted longicor...

    Keisuke Nagamine, Takumi Kayukawa, Sugihiko Hoshizaki, Takashi Matsuo in SpringerPlus (2014)