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Article
Open AccessDancing the Nanopore limbo – Nanopore metagenomics from small DNA quantities for bacterial genome reconstruction
While genome-resolved metagenomics has revolutionized our understanding of microbial and genetic diversity in environmental samples, assemblies of short-reads often result in incomplete and/or highly fragmente...
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Article
Open AccessOpen-label placebo treatment does not enhance cognitive abilities in healthy volunteers
The use of so-called ‘smart drugs’ such as modafinil to improve cognitive performance has recently attracted considerable attention. However, their side effects have limited user enthusiasm. Open-label placebo...
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Reference Work Entry In depth
Dementia Quality of Life Instrument
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Chapter and Conference Paper
Radiation Tolerant Reconfigurable Hardware Architecture Design Methodology
The purpose of this research topic is to investigate the properties of reconfigurable devices (i.e., FPGA) under a radiation environment to finally propose a new methodology to design and evaluate cost-effecti...
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Reference Work Entry In depth
Clinical Dementia Rating Scale
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Chapter
Postkoloniale Bildung
Postkoloniale Perspektiven bieten eine theoretische Orientierung für eine inklusivere, diversere, gerechtere und machtkritische Bildungspraxis. Im deutschsprachigen Raum gibt es zahlreiche interdisziplinäre In...
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Article
Open AccessCan positive expectations help to improve the learning of risk literacy? A cluster-randomized study in undergraduate medical students
Risk literacy, i.e., the ability to calculate and apply risk parameters, represents a key competence for risk communication and medical decision making. However, risk literacy is reportedly low in medical stud...
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Article
Open AccessAcquisition learning is stronger for aversive than appetitive events
Appetitive and aversive learning are both key building blocks of adaptive behavior, yet knowledge regarding their differences is sparse. Using a capsaicin heat pain model in 36 healthy participants, this study...
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Chapter
Stadt aneignen – Alltägliche Begegnungen, nachbarschaftliche Kollektive und soziale Bewegungen in globaler Perspektive
Aneignungen des städtischen Raums sind Akte, Dinge anders zu tun, als es normalerweise z. B. durch gebauten Raum, durch vorherrschende Geschlechterverhältnisse oder durch Gesetze vorgesehen ist. Damit spiegeln...
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Chapter
Zur Zukunftsfähigkeit des Wohlstands- und Wachstumsverständnisses
Der Entwicklungsprozess von Volkswirtschaften geht mit unter das Reproduktionsniveau sinkenden Geburtenraten einher. Hinzu kommt mit einer gewissen Verzögerung auch ein Rückgang des Wirtschaftswachstums. Durch...
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Article
Open AccessPreferences of patients with asthma or COPD for treatments in pulmonary rehabilitation
Pulmonary rehabilitation (PR) aims to improve disease control in patients with chronic obstructive pulmonary disease (COPD) and asthma. However, the success of PR-programs depends on the patients’ participatio...
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Article
Open AccessEffects of open-label placebos on test performance and psychological well-being in healthy medical students: a randomized controlled trial
Psychological distress is prevalent in students and can predispose to psychiatric disorders. Recent findings indicate that distress might be linked to impaired cognitive performance in students. Experimental f...
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Living Reference Work Entry In depth
Dementia Quality of Life Instrument
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Living Reference Work Entry In depth
Clinical Dementia Rating Scale
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Chapter
Digitalisierung der Arbeitswelt kommunaler Energieversorger
Ziel des Verbundprojekts AKTIV-kommunal war die Entwicklung, pilothafte Umsetzung und Evaluierung einer integrierten Toolbox für die digitale Transformation kommunaler Energieversorger. In drei integriert bear...
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Article
Open AccessA novel human pluripotent stem cell-based assay to predict developmental toxicity
There is a great need for novel in vitro methods to predict human developmental toxicity to comply with the 3R principles and to improve human safety. Human-induced pluripotent stem cells (hiPSC) are ideal for...
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Article
Copper and the brain noradrenergic system
Copper (Cu) plays an essential role in the development and function of the brain. In humans, genetic disorders of Cu metabolism may cause either severe Cu deficiency (Menkes disease) or excessive Cu accumulati...
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Article
Psychophysical effects of an exercise therapy during pediatric stem cell transplantation: a randomized controlled trial
This study evaluates the physical and psychosocial effects of an inpatient exercise program for children and adolescents undergoing hematopoietic stem cell transplantation (HSCT). Participants (n = 70) were rando...
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Article
Open AccessConditioned pain modulation in drug-naïve patients with de novo Parkinson’s disease
Pain is highly prevalent in patients with Parkinson’s disease (PD), but underlying pathophysiological mechanisms are largely unclear. In many chronic pain syndromes deficits in endogenous pain inhibition have ...
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Article
Exercise improves functional capacity and lean body mass in patients with gastrointestinal cancer during chemotherapy: a single-blind RCT
Although growing evidence underlines the benefits of physical activity as supportive intervention for cancer patients, sparse data are available for exercise in patients with advanced disease stages, in partic...
