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Article
Engineered materials for in vivo delivery of genome-editing machinery
Genome-editing technologies, such as CRISPR–Cas9, are promising for treating otherwise incurable genetic diseases. Great progress has been made for ex vivo genome editing; however, major bottlenecks exist in t...
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Article
Design considerations for an integrated microphysiological muscle tissue for drug and tissue toxicity testing
Microphysiological systems provide a tool to simulate normal and pathological function of organs for prolonged periods. These systems must incorporate the key functions of the individual organs and enable inte...
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Article
The Sustained Release of Galardin and Taxol from Gelatin Chondroitin Sulfate Coacervate Films
Coronary artery atherosclerosis is the leading cause of death in the United States. Restenosis following percutaneous transluminal balloon angioplasty (PTCA) remains the limiting factor in the use of this trea...
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Chapter
Ultrasonic Modulated Drug Delivery Systems
Considerable research efforts have been directed towards develo** attention has been paid to designing systems where the rate of delivery can be regulated externally. Nevertheless, there are a number of situ...
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Chapter
Manganese Nodule and Surface Sediment Compositions: DOMES Sites A, B, And C
Manganese nodules and associated sediment from the equatorial North Pacific have been examined to ascertain relations between nodule abundance, texture, and composition, and sediment composition, lithology and...
