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  1. No Access

    Article

    Population differences in S-warfarin pharmacokinetics among African Americans, Asians and whites: their influence on pharmacogenetic dosing algorithms

    Using population pharmacokinetic analysis (PPK), we attempted to identify predictors of S-warfarin clearance (CL(S)) and to clarify population differences in S-warfarin pharmacokinetics among a cohort of 378 Afri...

    K Kubo, M Ohara, M Tachikawa, L H Cavallari, M T M Lee in The Pharmacogenomics Journal (2017)

  2. No Access

    Article

    Low-dose thymoglobulin as second-line treatment for steroid-resistant acute GvHD: an analysis of the JSHCT

    A nationwide retrospective study for the clinical outcomes of 99 patients who had received thymoglobulin at a median total dose of 2.5 mg/kg (range, 0.5–18.5 mg/kg) as a second-line treatment for steroid-resis...

    M Murata, K Ikegame, Y Morishita, H Ogawa, K Kaida in Bone Marrow Transplantation (2017)

  3. No Access

    Article

    New muonium HFS measurements at J-PARC/MUSE

    At the Muon Science Facility (MUSE) of J-PARC (Japan Proton Accelerator Research Complex), the MuSEUM collaboration is planing new measurements of the ground state hyperfine structure (HFS) of muonium both at ...

    P. Strasser, M. Aoki, Y. Fukao, Y. Higashi, T. Higuchi, H. Iinuma in Hyperfine Interactions (2016)

  4. No Access

    Article

    Impact of HLA allele mismatch on the clinical outcome in serologically matched related hematopoietic SCT

    In unrelated hematopoietic SCT (HSCT), HLA allele mismatch has been shown to have a significant role. To clarify the importance of HLA allele mismatch in the GVH direction in related HSCT, we retrospectively e...

    S Fuji, J Kanda, S Kato, K Ikegame, S Morishima, T Miyamoto in Bone Marrow Transplantation (2014)

  5. No Access

    Article

    Magnetic ordering of spin systems having fractal dimensions Experimental study

    It is well-known that cooperative properties such as magnetic ordering can depend on the samples’ dimensions (Ds) in a qualitative way. However, there have been no samples with well-defined non-integer Ds. The d...

    T. Naito, H. Yamamoto, K. Okuda, K. Konishi, H. Mayama in The European Physical Journal B (2013)

  6. No Access

    Article

    Magnetic Phase Transitions in bcc 3He

    We study magnetic phase transitions in the bcc solid 3He by means of Monte Carlo simulations. We employ a classical spin model on the bcc lattice with multiple ring-exchange interactions. In the present study, we...

    S. Suzuki, T. Miura, K. Kubo in Journal of Low Temperature Physics (2012)

  7. Article

    Immunohistochemical localization of notch signaling molecules in ameloblastomas

    We examined Notch signaling molecules, Notch1 and Jagged1, in serial large cases of typical solid/multicystic ameloblastoma. In general, Notch positive staining products were frequently detected in the cytopla...

    E Muraki, K Nakano, H Maeda, M Takayama, M **no in European Journal of Medical Research (2011)

  8. No Access

    Article

    Development of a Thermoelectric Module Using the Heusler Alloy Fe2VAl

    A thermoelectric module was constructed using a Heusler Fe2VAl sintered alloy prepared by pulse-current sintering (PCS) using mechanically alloyed powder. A large-amplitude vibration mill was developed for powder...

    M. Mikami, K. Kobayashi, T. Kawada, K. Kubo, N. Uchiyama in Journal of Electronic Materials (2009)

  9. No Access

    Chapter

    Interactions Between Chewing and Brain Activity in Humans

    The involvement of chewing in brain activity in humans has been studied. In our studies using functional magnetic resonance imaging (fMRI) and behavioral techniques, chewing resulted in a bilateral increase in...

    M. Onozuka, Y. Hirano, A. Tachibana, W. Kim, Y. Ono in Novel Trends in Brain Science (2008)

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    Article

    Identification of Ki23819, a highly potent inhibitor of kinase activity of mutant FLT3 receptor tyrosine kinase

    Constitutively active internal tandem duplication (ITD) in the juxtamembrane domain of Fms-like tyrosine kinase 3 (FLT3), a type III receptor tyrosine kinase, is the most common molecular defect associated wit...

    Y Komeno, M Kurokawa, Y Imai, M Takeshita, T Matsumura, K Kubo, T Yoshino in Leukemia (2005)

  11. No Access

    Article

    Transport and Optical Properties of Diluted Magnetic Semiconductors

    We investigated the transport and optical properties of diluted magnetic semiconductors theoretically by using a simple model where carriers move in a single band. In this model the carrier feels a nonmagnetic...

    K. Kagami, M. Takahashi, K. Kubo in Journal of Superconductivity (2005)

  12. No Access

    Article

    Intraspecific behaviors and major cheliped sexual dimorphism in three congeneric callianassid shrimp

    Decapod callianassid shrimps are usually solitary occupants of their burrows. They are known to show distinct sexual dimorphism of the major cheliped, which is used as a weapon for intraspecific fighting. Thre...

    K. Shimoda, Y. Wardiatno, K. Kubo, A. Tamaki in Marine Biology (2005)

  13. No Access

    Article

    The reduced height genes do not affect the root penetration ability in wheat

    Root penetration (RP) ability into compacted soil is an important breeding target for drought avoidance by durum (Triticum turgidum L. var. durum) and bread wheat (T. aestivum L.) in regions with compacted soils ...

    K. Kubo, Y. Jitsuyama, K. Iwama, N. Watanabe, A. Yanagisawa, I. Elouafi in Euphytica (2005)

  14. No Access

    Article

    Genotypic difference in root penetration ability by durum wheat (Triticum turgidum L. var. durum) evaluated by a pot with paraffin-Vaseline discs

    Improvement of root penetration (RP) ability in durum wheat (Triticum turgidum L. var. durum) is an important breeding target to reduce yield losses due to soil compaction and drought. This study investigated the...

    K. Kubo, Y. Jitsuyama, K. Iwama, T. Hasegawa, N. Watanabe in Plant and Soil (2004)

  15. No Access

    Article

    Systemic lupus erythematosus and thrombotic thrombocytopenic purpura: a case report and literature review

    We describe a patient with systemic lupus erythematosus (SLE) who developed severe and acute thrombotic thrombocytopenic purpura (TTP). Detection of the fragmentation of peripheral red blood cells (RBC) helped...

    K. Hamasaki, T. Mimura, H. Kanda, K. Kubo, K. Setoguchi, T. Satoh in Clinical Rheumatology (2003)

  16. No Access

    Article

    Spongy matrix of hyaluronic acid and collagen as a cultured dermal substitute: evaluation in an animal test

     The authors have developed a two-layered spongy matrix composed of hyaluronic acid (HA) and atelo-collagen (Col) as a cultured dermal substitute (CDS). This spongy matrix was applied to a full-thickness skin ...

    K. Kubo, Y. Kuroyanagi in Journal of Artificial Organs (2003)

  17. No Access

    Article

    Effects of an Eosinophil Chemotaxis Inhibitor, TAK-661, on Antigen-Induced Asthmatic Responses in Allergic Sheep

    Eosinophils have been shown to play a role in allergen-induced airway responses. The aim in this study was to examine the effects of TAK-661, a newly developed product as a specific inhibitory agent of eosinop...

    K. Fujimoto, T. Tsunoda, T. Koizumi, K. Kubo in Lung (2002)

  18. No Access

    Article

    Effect of series elasticity on isokinetic torque–angle relationship in humans

    The influence of muscle series elasticity on the relationship between torque and joint angle during dynamic contractions was studied. The torque–angle relationship during the maximal isokinetic knee extension...

    Y. Kawakami, K. Kubo, H. Kanehisa, T. Fukunaga in European Journal of Applied Physiology (2002)

  19. No Access

    Chapter and Conference Paper

    MÖssbauer Spectroscopic Study on Characterization of Iron in the Permian to Triassic Deep-Sea Chert from Japan

    Chemical states of iron in the Permian to Triassic deep-sea chert from Japan have been investigated by 57Fe Mössbauer spectroscopy. In the 57Fe Mössbauer spectra five iron species were identified, that is, hemati...

    M. Matsuo, K. Kubo, Y. Isozaki in Hyperfine Interactions (C) (2002)

  20. No Access

    Chapter

    Magnetism and Electronic States of Systems with Strong Hund Coupling

    We discussed two topics on the Hund coupling in lattice systems employing simplified models. First we examined the effectiveness of the Hund coupling in realizing ferromagnetism in the doubly degenerate Hubbar...

    K. Kubo, D. M. Edwards, A. C. M. Green, T. Momoi, H. Sakamoto in Physics of Manganites (2002)

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