27 Result(s)

Article

IKZF1 deletion is enriched in pediatric B-cell precursor acute lymphoblastic leukemia patients showing prednisolone resistance

T Imamura, M Yano, D Asai, A Moriya-Saito, S-I Suenobu, D Hasegawa, T Deguchi… in Leukemia (2016)

Article

Adverse prognostic impact of KIT mutations in childhood CBF-AML: the results of the Japanese Pediatric Leukemia/Lymphoma Study Group AML-05 trial

M Tokumasu, C Murata, A Shimada, K Ohki, Y Hayashi, A M Saito, J Fujimoto… in Leukemia (2015)

Article

High expression of EVI1 and MEL1 is a compelling poor prognostic marker of pediatric AML

EVI1 and MEL1 are homolog genes whose transcriptional activations by chromosomal translocations are known in small subsets of leukemia. From gene expression profiling data of 130 Japanese pediatric acute myeloid ...

A Jo, S Mitani, N Shiba, Y Hayashi, Y Hara, H Takahashi, I Tsukimoto, A Tawa… in Leukemia (2015)

Article

Early use of allogeneic hematopoietic stem cell transplantation for infants with MLL gene-rearrangement-positive acute lymphoblastic leukemia

Sixty-two infants with MLL gene-rearrangement-positive acute lymphoblastic leukemia (MLL-r ALL) were treated with the MLL03 protocol of the Japanese Pediatric Leukemia/Lymphoma Study Group: short-course intensive...

K Koh, D Tomizawa, A Moriya Saito, T Watanabe, T Miyamura, M Hirayama… in Leukemia (2015)

Article

Excess treatment reduction including anthracyclines results in higher incidence of relapse in core binding factor acute myeloid leukemia in children

D Tomizawa, A Tawa, T Watanabe, A M Saito, K Kudo, T Taga, S Iwamoto, A Shimada… in Leukemia (2013)

Article

Comparison of matched-sibling donor BMT and unrelated donor BMT in children and adolescent with acquired severe aplastic anemia

From January 1991 to March 2007, 61 children and adolescent with acquired severe aplastic anemia received BMT in our institutions. We retrospectively compared the outcome of 30 cases of matched-sibling donor B...

H Yagasaki, Y Takahashi, A Hama, K Kudo, N Nishio… in Bone Marrow Transplantation (2010)

Article

Relationship between tacrolimus blood concentrations and clinical outcome during the first 4 weeks after SCT in children

The relationship between tacrolimus concentration and acute GVHD is not well known, with few published data available for lower target levels. We hypothesized that lower levels of tacrolimus would correlate wi...

N Watanabe, K Matsumoto, H Muramatsu, K Horibe, T Matsuyama… in Bone Marrow Transplantation (2010)

Article

Outcome of risk-based therapy for infant acute lymphoblastic leukemia with or without an MLL gene rearrangement, with emphasis on late effects: a final report of two consecutive studies, MLL96 and MLL98, of the Japan Infant Leukemia Study Group

We evaluated the efficacy of a treatment strategy in which infants with acute lymphoblastic leukemia (ALL) were stratified by their MLL gene status and then assigned to different risk-based therapies. A total of ...

D Tomizawa, K Koh, T Sato, N Kinukawa, A Morimoto, K Isoyama, Y Kosaka, T Oda… in Leukemia (2007)

Article

N822 mutation of KIT gene was frequent in pediatric acute myeloid leukemia patients with t(8;21) in Japan: a study of the Japanese childhood AML cooperative study group

A Shimada, T Taki, C Kubota, T Itou, A Tawa, K Horibe, M Tsuchida, R Hanada… in Leukemia (2007)

Article

No nucleophosmin mutations in pediatric acute myeloid leukemia with normal karyotype: a study of the Japanese Childhood AML Cooperative Study Group

A Shimada, T Taki, C Kubota, A Tawa, K Horibe, M Tsuchida, R Hanada… in Leukemia (2007)

Article

The Seventh International Childhood Acute Lymphoblastic Leukemia Workshop Report: Palermo, Italy, January 29–30, 2005

Between 1995 and 2004, six International Childhood Acute Lymphoblastic Leukemia (ALL) Workshop have been held, and the completion of several collaborative projects has established the clinical relevance and tr...

M Aricó, A Baruchel, Y Bertrand, A Biondi, V Conter, T Eden, H Gadner, P Gaynon… in Leukemia (2005)

Article

Clinicopathologic characteristics of leukemia in Japanese children and young adults

The aim of this study is to clarify the clinicopathologic characteristics of adolescent leukemia in Japan by retrospective analysis. Patients with acute lymphoblastic leukemia (ALL), acute myelogenous leukemia...

K Horibe, I Tsukimoto, R Ohno in Leukemia (2001)

Article

Correlation between HHV-6 infection and skin rash after allogeneic bone marrow transplantation

We investigated whether a causal relationship exists between human herpesvirus 6 (HHV-6) and skin rash resembling acute graft-versus-host disease (GVHD) following bone marrow transplantation (BMT). Isolation o...

T Yoshikawa, M Ihira, M Ohashi, S Suga, Y Asano, H Miyazaki… in Bone Marrow Transplantation (2001)

Article

Risk factors for chronic graft-versus-host disease after allogeneic stem cell transplantation in children

We analyzed the incidence and risk factors for chronic graft-versus-host disease (GVHD) in 265 children undergoing allogeneic stem cell transplantation (SCT) who survived longer than 3 months post SCT. Patient...

M Kondo, S Kojima, K Horibe, K Kato, T Matsuyama in Bone Marrow Transplantation (2001)

Article

Monitoring four herpesviruses in unrelated cord blood transplantation

Cord blood transplantation, which has lower risk of graft-versus-host disease than bone marrow transplantation, might have higher risk of infections. A system to quantify four herpesviruses, CMV, human herpesv...

N Tanaka, H Kimura, Y Hoshino, K Kato, T Yoshikawa, Y Asano… in Bone Marrow Transplantation (2000)

Article

Allogeneic hematopoietic transplantation of CD34⁺ selected cells from an HLA haplo-identical related donor. A long-term follow-up of 135 patients and a comparison of stem cell source between the bone marrow and the peripheral blood

We studied the outcome of allogeneic transplants in 135 patients who received selected BM and/or PBSC CD34⁺ cells from HLA haplo-identical related donors. Donor engraftment was achieved in 108 of 128 evaluable tr...

S Kato, H Yabe, M Yasui, K Kawa, T Yoshida, A Watanabe… in Bone Marrow Transplantation (2000)

Article

Veno-occlusive disease of the liver after allogeneic bone marrow transplantation in children with hematologic malignancies: incidence, onset time and risk factors

One hundred and forty children with hematologic malignancies undergoing allogeneic BMT were reviewed in order to clarify the incidence, onset time, and risk factors for veno-occlusive disease (VOD) of the live...

S Hasegawa, K Horibe, T Kawabe, K Kato, S Kojima… in Bone Marrow Transplantation (1998)