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Article
Open AccessIFNΛ3/4 locus polymorphisms and IFNΛ3 circulating levels are associated with COPD severity and outcomes
Interferon lambdas (IFNLs) have important anti-viral/bacterial and immunomodulatory functions in the respiratory tract. How do IFNLs impact COPD and its exacerbations?
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Article
Open AccessMannose-binding lectin protein and its association to clinical outcomes in COPD: a longitudinal study
Functional deficiency of mannose-binding lectin (MBL) may contribute to the pathogenesis of chronic obstructive pulmonary disease. We hypothesized that specific MBL2 gene polymorphisms and circulating MBL prot...
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Article
Open AccessAnti-fibrotic effects of nintedanib in lung fibroblasts derived from patients with idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with poor prognosis. The kinase inhibitor nintedanib specific for vascular endothelial growth factor receptor (VEGFR), platelet-derived growth ...
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Article
Effect of airborne Alternaria conidia, ozone exposure, PM10 and weather on emergency visits for asthma in school-age children in Kolkata city, India
Alternaria is one of the important allergenic fungal spores having special role in childhood asthma. Aerodynamic particle of <10 μm diameter (PM10) and ozone exacerbate respiratory conditions inc...
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Article
Aerobiological, clinical, and immunobiochemical studies on Alstonia scholaris pollen from eastern India
Alstonia scholaris or Indian devil tree is a common, evergreen, tropical tree of the Apocynaceae family. The objectives of this study were (a) to observe the seasonal variation of A. scholaris po...
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Article
Airborne load of Cassia pollen in West Bengal, eastern India: its atmospheric variation and health impact
A Burkard personal volumetric sampler was used at Sriniketan, a town about 150 km northwest of Calcutta, in the state of West Bengal, in eastern India to record the frequency of three common airborne Cassia polle...
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Article
Aerobiological, clinical and immunobiochemical studies on Lantana camara pollen and cross-reactivity with other Verbenaceae pollen species
Airborne pollen is an important and potent source of aeroallergens. The aim of the study was to conduct a 2-year aerobiological survey in Calcutta, India, for knowing the concentration and seasonal periodicity...
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Article
Open AccessImmediate Hypersensitivity to Common Food Allergens: An Investigation on Food Sensitization in Respiratory Allergic Patients of Calcutta, India
Food allergy may be defined as an immunoglobulin E-mediated immune response to food proteins. Such studies have previously not been done in Calcutta, India. The present study was therefore undertaken to record...
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Article
Prevalence of allergenic pollen grains in the aerosol of the city of Calcutta, India: a two year study
The role of pollen grains as a causative agent of respiratory allergic disorders such as asthma and allergic rhinitis is common and very well established. The aim of this study was to assess the frequencies of...