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Article
Open AccessPeripheral arterial tonometry versus polysomnography in suspected obstructive sleep apnoea
Polysomnography (PSG) is the gold standard for the diagnosis of obstructive sleep apnoea (OSA). Home sleep apnoea testing with peripheral arterial tonometry (PAT) is a recommended diagnostic alternative for pa...
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Article
Open AccessOxygen desaturation during flexible bronchoscopy with propofol sedation is associated with sleep apnea: the PROSA-Study
Obstructive sleep apnea (OSA) is characterized by repetitive episodes of complete or partial obstruction of the upper airways during sleep. Conscious sedation for flexible bronchoscopy (FB) places patients in ...
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Article
Open AccessLaryngopharyngeal reflux in chronic obstructive pulmonary disease - a multi-centre study
Reflux of gastric content has been associated with recurrent exacerbations of chronic obstructive pulmonary disease (COPD). We aimed to assess the prevalence of laryngopharyngeal reflux (LPR) in COPD and if LP...
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Article
Open AccessEndothelial dysfunction is not a predictor of outcome in chronic obstructive pulmonary disease
Local airway inflammation may cause systemic changes which result in endothelial dysfunction. Only a few studies have used reactive hyperemia peripheral arterial tonometry (RH-PAT) in patients with chronic obs...
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Article
Open AccessMultiplex bacterial polymerase chain reaction in a cohort of patients with pleural effusion
The identification of the pathogens in pleural effusion has mainly relied on conventional bacterial culture or single species polymerase chain reaction (PCR), both with relatively low sensitivity. We investiga...
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Article
Open AccessIFNΛ3/4 locus polymorphisms and IFNΛ3 circulating levels are associated with COPD severity and outcomes
Interferon lambdas (IFNLs) have important anti-viral/bacterial and immunomodulatory functions in the respiratory tract. How do IFNLs impact COPD and its exacerbations?
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Chapter
Erratum to Chapter 11: Interleukin-Targeted Therapy for Metabolic Syndrome and Type 2 Diabetes
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Chapter
Interleukin-Targeted Therapy for Metabolic Syndrome and Type 2 Diabetes
Interleukin-1β (IL-1β) is a key regulator of the body’s inflammatory response and is produced after infection, injury, and an antigenic challenge. Cloned in 1984, the single polypeptide IL-1β has been shown t...
